MARCHF8 and ARR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MARCHF8	ARR3
Description		membrane associated ring-CH-type finger 8	arrestin 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cell Projection Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity MHC Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Protein Polyubiquitination Adaptive Immune Response Immune System Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response Protein Ubiquitination	G Protein-coupled Receptor Internalization Endocytosis Signal Transduction Visual Perception
Pathways
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ARR3 CD86 CGAS CYB5B FA2H FUBP3 GOSR2 HNRNPA1 HNRNPK IL1RAP TMEM14C UBC UBE2D1 UBE2D3 UBE2H VAMP2	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		220972	407
HPRD ID		17466	02358
Ensembl ID		ENSG00000165406	ENSG00000120500
Uniprot IDs		Q5T0T0	P36575
PDB IDs		2D8S
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination	Photoreceptor Activity G Protein-coupled Photoreceptor Activity Thermotaxis Photoreceptor Disc Membrane G Protein-coupled Receptor Activity Detection Of Visible Light Sperm Head Plasma Membrane Absorption Of Visible Light Phototransduction Detection Of Temperature Stimulus Involved In Thermoception 11-cis Retinal Binding G Protein-coupled Receptor Signaling Pathway Response To Temperature Stimulus Detection Of Light Stimulus Positive Regulation Of MAPK Cascade Lysosome Transcytosis Regulation Of Organelle Organization Cellular Response To Light Stimulus Detection Of Temperature Stimulus Involved In Sensory Perception Uterus Development Clathrin-coated Endocytic Vesicle Detection Of Temperature Stimulus Bone Resorption Detection Of Abiotic Stimulus Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Light Stimulus Enzyme Binding Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Vacuolar Transport Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Bone Remodeling Regulation Of Bone Resorption Follicle-stimulating Hormone Receptor Activity Regulation Of Acetylcholine Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Radiation Rod Bipolar Cell Differentiation RNA Polymerase III General Transcription Initiation Factor Binding Glycine N-methyltransferase Activity Positive Regulation Of ERK1 And ERK2 Cascade Visual Perception Sensory Perception Of Light Stimulus Regulation Of Macroautophagy Response To Radiation Protein Targeting To Vacuole Vasodilation Fc Receptor Signaling Pathway
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