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MARCHF8

Description membrane associated ring-CH-type finger 8
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Cytoplasm
  • Lysosome
  • Lysosomal Membrane
  • Endosome
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Golgi Apparatus
  • Membrane
  • Cytoplasmic Vesicle Membrane
  • Cytoplasmic Vesicle
  • Early Endosome Membrane
  • Late Endosome Membrane
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Zinc Ion Binding
  • Transferase Activity
  • MHC Protein Binding
  • Metal Ion Binding
  • Ubiquitin Protein Ligase Activity
Biological Process
  • Protein Polyubiquitination
  • Adaptive Immune Response
  • Immune System Process
  • Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
  • Immune Response
  • Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Interacting Genes 16 interacting genes: ARR3 CD86 CGAS CYB5B FA2H FUBP3 GOSR2 HNRNPA1 HNRNPK IL1RAP TMEM14C UBC UBE2D1 UBE2D3 UBE2H VAMP2
Entrez ID 220972
HPRD ID 17466
Ensembl ID ENSG00000165406
Uniprot IDs Q5T0T0
PDB IDs 2D8S
Enriched GO Terms of Interacting Partners?
  • Ubiquitin Conjugating Enzyme Activity
  • Protein K48-linked Ubiquitination
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