MTMR3 and HIVEP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MTMR3	HIVEP1
Gene Name		myotubularin related protein 3	human immunodeficiency virus type I enhancer binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Extrinsic Component Of Membrane	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Metal Ion Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Dephosphorylation Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Peptidyl-tyrosine Dephosphorylation Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) IgA nephropathy ( 22197929) Inflammatory bowel disease ( 23128233) Inflammatory bowel disease (early onset) ( 19915574) Lung cancer ( 21725308) Nephropathy ( 21399633)	Alcohol and nictotine co-dependence ( 22488850)
Protein-Protein Interactions		1 interactors: HIVEP1	35 interactors: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A DNAJA1 EMG1 GAA GSDMB HPD HRSP12 HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 STAT3 TMEM176A
Entrez ID		8897	3096
HPRD ID		09151	01925
Ensembl ID		ENSG00000100330	ENSG00000095951
Uniprot IDs		Q13615	P15822
PDB IDs			1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?			Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cell Death Regulation Of Cell Death Neurotrophin Signaling Pathway Regulation Of Signaling Regulation Of Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stress Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Growth Regulation Of Phosphorylation Glucose Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cell Death Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Hexose Metabolic Process Positive Regulation Of Organelle Organization
Tagcloud ?			16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Difference) ?			16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40
Tagcloud (Intersection) ?