HIVEP1 and GAA

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HIVEP1	GAA
Gene Name		human immunodeficiency virus type I enhancer binding protein 1	glucosidase, alpha; acid
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion	Lysosome Lysosomal Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Alpha-1,4-glucosidase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Maltose Metabolic Process Regulation Of The Force Of Heart Contraction Diaphragm Contraction Heart Morphogenesis Glycogen Catabolic Process Sucrose Metabolic Process Glucose Metabolic Process Lysosome Organization Locomotory Behavior Tissue Development Vacuolar Sequestering Muscle Cell Cellular Homeostasis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Cardiac Muscle Contraction
Pathways
Drugs			Acarbose Miglitol
Diseases
GWAS		Alcohol and nictotine co-dependence ( 22488850)
Protein-Protein Interactions		35 interactors: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BHLHE40 BNIP3 BRCA1 CACNA1A DNAJA1 EMG1 GAA GSDMB HPD HRSP12 HSPA1A IMMT MAGED1 MAPK14 MAPK8 MTMR3 NHLH1 NINJ1 NUCB1 PRKAR1A RAB1A SDCBP SERTAD1 SMAD3 SNX4 SOCS3 SOX10 STAT3 TMEM176A	5 interactors: EP300 HIVEP1 NCF1 NUMBL STAT2
Entrez ID		3096	2548
HPRD ID		01925	06006
Ensembl ID		ENSG00000095951	ENSG00000171298
Uniprot IDs		P15822	P10253
PDB IDs		1BBO 3ZNF 4ZNF
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cell Death Regulation Of Cell Death Neurotrophin Signaling Pathway Regulation Of Signaling Regulation Of Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Stress Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Growth Regulation Of Phosphorylation Glucose Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Cell Death Death Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cell Death Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Hexose Metabolic Process Positive Regulation Of Organelle Organization	Interaction With Symbiont Histone H2B Acetylation Innate Immune Response Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Neuroblast Division In Subventricular Zone Regulation Of Tubulin Deacetylation Respiratory Burst Involved In Defense Response Response To Yeast Cell Surface Receptor Signaling Pathway Immune Response Killing By Host Of Symbiont Cells Defense Response Hydrogen Peroxide Biosynthetic Process Positive Regulation By Host Of Viral Transcription N-terminal Protein Amino Acid Acetylation Respiratory Burst Forebrain Neuroblast Division Negative Regulation Of Smooth Muscle Contraction Cytokine-mediated Signaling Pathway Superoxide Anion Generation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Neutrophil Mediated Immunity Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Muscle Contraction Lateral Ventricle Development Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Killing Of Cells Of Other Organism Somatic Stem Cell Division Cellular Response To Cytokine Stimulus N-terminal Protein Amino Acid Modification Defense Response To Fungus Regulation Of Cellular Response To Heat Immune System Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Leukocyte Mediated Cytotoxicity Hydrogen Peroxide Metabolic Process Leukotriene Metabolic Process Biosynthetic Process Positive Regulation Of Dendrite Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Transcription, DNA-templated Response To Cytokine Response To Fungus Response To Other Organism Regulation Of Type I Interferon-mediated Signaling Pathway
Tagcloud ?		16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40	birds corrected correction deficient endocytic endocytosed endocytosis existed fibroblasts glucosidase glycogen hamster illustrate kd lasted lethal lysosomes maltase mammals man myoblasts nmol normalize normalized ovary pompe quail replacement subfractions
Tagcloud (Difference) ?		16q22 aboriginal cholestasis cirh1a cirhin cirip cirrhosis collaboration evolves focuses helped hopital indian justine mapped naic nations northwestern nucleolus portal quebec r565w researchers splice ste tex292 twelve varices wd40	birds corrected correction deficient endocytic endocytosed endocytosis existed fibroblasts glucosidase glycogen hamster illustrate kd lasted lethal lysosomes maltase mammals man myoblasts nmol normalize normalized ovary pompe quail replacement subfractions
Tagcloud (Intersection) ?