SSBP1 and GCM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSBP1	GCM2
Description		single stranded DNA binding protein 1	glial cells missing transcription factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Exosome	Chromatin Nucleus
	Molecular Function	DNA Binding Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding Enzyme Activator Activity Identical Protein Binding Protein Homodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Replication DNA-templated DNA Replication Positive Regulation Of Helicase Activity Protein Homotetramerization Positive Regulation Of Mitochondrial DNA Replication	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Intracellular Calcium Ion Homeostasis Intracellular Phosphate Ion Homeostasis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Parathyroid Gland Development
Pathways		Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation Strand-asynchronous mitochondrial DNA replication
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457)	Menarche and menopause (age at onset) ( 19448621) Metabolite levels ( 23823483) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		13 interacting genes: CDK1 CEBPA CKS1B CKS2 FOXP1 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG TP53 YWHAQ	34 interacting genes: CEACAM6 CRX DOK3 ECM1 FHL3 GPSM1 GSC2 HOXA1 HSF2BP HSFY1 HSFY2 JMJD7 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 LHX3 MEOX2 MYOZ3 PAX6 PAX8 PLEKHG4 POU6F2 RBPMS RUSC1 SSBP1 TBX19 TOX3 TRAF1 USP54 WWOX YPEL3 ZMIZ2 ZNF34
Entrez ID		6742	9247
HPRD ID		02703	04758
Ensembl ID		ENSG00000106028	ENSG00000124827
Uniprot IDs		A4D1U3 B7Z268 Q04837	O75603
PDB IDs		1S3O 2DUD 3ULL 6RUP 8UZT
Enriched GO Terms of Interacting Partners?		Chromatin Binding Fibroblast Proliferation Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleobase-containing Compound Biosynthetic Process Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Mitochondrial DNA Metabolic Process Core Promoter Sequence-specific DNA Binding Negative Regulation Of Stem Cell Proliferation DNA-templated Transcription Protein-containing Complex Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity 14-3-3 Protein Binding Regulation Of RNA Metabolic Process Pronuclear Fusion Mitotic DNA-templated DNA Replication Regulation Of DNA-templated Transcription Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Cell Differentiation Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic DNA Integrity Checkpoint Signaling Cyclin B1-CDK1 Complex Macromolecule Biosynthetic Process Cell Population Proliferation Cyclin A1-CDK1 Complex Regulation Of Heart Growth DNA-templated DNA Replication DNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Cyclin A2-CDK1 Complex Cyclin-dependent Protein Kinase Activity Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell Cycle Transcription Regulator Complex Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Stem Cell Proliferation Regulation Of Stem Cell Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mononuclear Cell Differentiation Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 C/EBP Complex SCF Ubiquitin Ligase Complex DNA Replication Proofreading	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Sequence-specific DNA Binding Pituitary Gland Development Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Inner Ear Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Fate Specification Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process SMAD Protein Signal Transduction
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