SSBP1 and LGALS7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSBP1	LGALS7
Description		single stranded DNA binding protein 1	galectin 7
Image
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Exosome
	Molecular Function	DNA Binding Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding Enzyme Activator Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	DNA Replication DNA-templated DNA Replication Positive Regulation Of Helicase Activity Protein Homotetramerization Positive Regulation Of Mitochondrial DNA Replication
Pathways		Transcriptional activation of mitochondrial biogenesis Mitochondrial protein degradation Strand-asynchronous mitochondrial DNA replication	Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs			Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Anorexia nervosa ( 23568457)	Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		13 interacting genes: CDK1 CEBPA CKS1B CKS2 FOXP1 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG TP53 YWHAQ	8 interacting genes: CA12 CDC42 HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2
Entrez ID		6742	3963
HPRD ID		02703	09002
Ensembl ID		ENSG00000106028	ENSG00000205076
Uniprot IDs		A4D1U3 B7Z268 Q04837	P47929
PDB IDs		1S3O 2DUD 3ULL 6RUP 8UZT	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S 6VTO 6VTP 6VTQ 6VTR 6VTS 7N4O 7N57 7N6C 7N8D 7N8G 7N96 7RDG 7TKW 7TKX 7TKY 7TKZ 7TRN 7TRO 7XAC 7XBL
Enriched GO Terms of Interacting Partners?		Chromatin Binding Fibroblast Proliferation Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleobase-containing Compound Biosynthetic Process Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Mitochondrial DNA Metabolic Process Core Promoter Sequence-specific DNA Binding Negative Regulation Of Stem Cell Proliferation DNA-templated Transcription Protein-containing Complex Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity 14-3-3 Protein Binding Regulation Of RNA Metabolic Process Pronuclear Fusion Mitotic DNA-templated DNA Replication Regulation Of DNA-templated Transcription Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Cell Differentiation Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic DNA Integrity Checkpoint Signaling Cyclin B1-CDK1 Complex Macromolecule Biosynthetic Process Cell Population Proliferation Cyclin A1-CDK1 Complex Regulation Of Heart Growth DNA-templated DNA Replication DNA Biosynthetic Process Regulation Of Mitotic Cell Cycle Cyclin A2-CDK1 Complex Cyclin-dependent Protein Kinase Activity Mitotic DNA Damage Checkpoint Signaling Regulation Of Cell Cycle Transcription Regulator Complex Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Stem Cell Proliferation Regulation Of Stem Cell Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Mononuclear Cell Differentiation Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 C/EBP Complex SCF Ubiquitin Ligase Complex DNA Replication Proofreading
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