SSBP1 and CKS1B

Number of citations of the paper that reports this interaction (PMID 19786724)
4

Data Source:
BioGRID (pull down)

		SSBP1	CKS1B
Gene Name		single-stranded DNA binding protein 1, mitochondrial	CDC28 protein kinase regulatory subunit 1B
Image
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	Chromatin Binding Single-stranded DNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	DNA Replication Organelle Organization Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Proliferation Cell Division
Pathways		Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Cyclin D associated events in G1 SCF(Skp2)-mediated degradation of p27/p21 G1/S Transition G1 Phase Cyclin E associated events during G1/S transition SCF(Skp2)-mediated degradation of p27/p21 S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457)	Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: CDK1 CKS1B CKS2 LDB1 POLG YWHAQ	34 interactors: ARID5A CCNA1 CCNA2 CCNB2 CDC27 CDC37 CDK1 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 HSP90AA1 IKZF1 KIAA0368 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPT3 SKP1 SKP2 SPERT SSBP1 SUMO1P1 TCF4 TRIM27 XIAP
Entrez ID		6742	1163
HPRD ID		02703	00299
Ensembl ID		ENSG00000106028	ENSG00000173207
Uniprot IDs		A4D1U3 B7Z268 Q04837	P61024 Q5T178
PDB IDs		1S3O 2DUD 3ULL	1BUH 1DKS 1DKT 2ASS 2AST
Enriched GO Terms of Interacting Partners?		Cell Division Histone H3-K4 Acetylation Pronuclear Fusion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Protein Kinase Activity G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Intracellular Transport Cell Cycle Process Regulation Of Protein Phosphorylation Base-excision Repair, Gap-filling Regulation Of Schwann Cell Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Protein Localization To Kinetochore Negative Regulation Of Erythrocyte Differentiation Aging Protein Localization To Chromosome, Centromeric Region Regulation Of Phosphorylation Positive Regulation Of Protein Import Into Nucleus, Translocation Mitochondrial DNA Replication Cell Cycle Organelle Organization Cerebellar Purkinje Cell Differentiation Histone Modification Regulation Of Phosphorus Metabolic Process Regulation Of Protein Import Into Nucleus, Translocation Cerebellar Purkinje Cell Layer Morphogenesis Mitotic G2 DNA Damage Checkpoint Regulation Of Intracellular Transport Ventricular Cardiac Muscle Cell Development Epithelial Structure Maintenance Mitochondrial DNA Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Cycle Process Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Cell Division Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Mitotic Cell Cycle Checkpoint Regulation Of Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Regulation Of Protein Kinase Activity Mitotic DNA Integrity Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Kinase Activity Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Protein Catabolic Process
Tagcloud ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized	axis biomarker cascade chemoresistance chemoresistant discoveries doi drive escape exerts gained immunoinhibitory inversely l1 l1highdrug mechanistic microrna mimic mir mt nsclc pd platinum programmed promotion sensitizes stat3 tumorigenicity worse
Tagcloud (Difference) ?		agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized	axis biomarker cascade chemoresistance chemoresistant discoveries doi drive escape exerts gained immunoinhibitory inversely l1 l1highdrug mechanistic microrna mimic mir mt nsclc pd platinum programmed promotion sensitizes stat3 tumorigenicity worse
Tagcloud (Intersection) ?