LDB1 and LHX6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LDB1	LHX6
Gene Name		LIM domain binding 1	LIM homeobox 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Protein Complex	Nucleus
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association	Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of DNA-templated Transcription, Elongation Somatic Stem Cell Maintenance Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hemoglobin Biosynthetic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cerebral Cortex Radially Oriented Cell Migration Cerebral Cortex Tangential Migration Cerebral Cortex GABAergic Interneuron Migration Forebrain Neuron Fate Commitment Cell Maturation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ATXN1 CTDSP1 ESR1 IRAK3 ISL1 LHX2 LHX3 LHX6 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	1 interactors: LDB1
Entrez ID		8861	26468
HPRD ID		09144	10498
Ensembl ID		ENSG00000198728	ENSG00000106852
Uniprot IDs		Q86U70	Q9UPM6
PDB IDs		2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Central Nervous System Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Central Nervous System Development Cellular Metabolic Process Brain Development Head Development Developmental Process Organ Development Anatomical Structure Development Forebrain Development Tube Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Specification Process Cell Differentiation Negative Regulation Of Signal Transduction Multicellular Organismal Development Neuron Differentiation Anatomical Structure Morphogenesis System Development Spinal Cord Motor Neuron Differentiation Generation Of Neurons Negative Regulation Of Signaling Transcription From RNA Polymerase II Promoter Neurogenesis	Histone H3-K4 Acetylation Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Hemoglobin Biosynthetic Process Negative Regulation Of Erythrocyte Differentiation Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Epithelial Structure Maintenance Cerebellar Cortex Formation Cell Differentiation In Hindbrain Cerebellar Purkinje Cell Layer Development Regulation Of Erythrocyte Differentiation Cerebellar Cortex Morphogenesis Histone H3 Acetylation Cerebellum Morphogenesis Regulation Of DNA-templated Transcription, Elongation Hindbrain Morphogenesis Gastrulation With Mouth Forming Second Cerebellar Cortex Development Somatic Stem Cell Maintenance Anterior/posterior Axis Specification Negative Regulation Of Myeloid Cell Differentiation Hair Follicle Development Hair Cycle Process Hair Cycle Histone Acetylation Axis Specification Cerebellum Development Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Metencephalon Development Protein Acetylation Stem Cell Maintenance Hindbrain Development Regulation Of Myeloid Cell Differentiation Tissue Homeostasis Gastrulation Central Nervous System Neuron Differentiation Skin Development Multicellular Organismal Homeostasis Stem Cell Development Anterior/posterior Pattern Specification Peptidyl-lysine Modification Epidermis Development Wnt Signaling Pathway Stem Cell Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Immune System Process Histone Modification
Tagcloud ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Difference) ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Intersection) ?