GMPS and SUMO4

Number of citations of the paper that reports this interaction (PMID 16236267)
15

Data Source:
HPRD (in vivo)

		GMPS	SUMO4
Gene Name		guanine monphosphate synthase	small ubiquitin-like modifier 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus
	Molecular Function	GMP Synthase Activity GMP Synthase (glutamine-hydrolyzing) Activity ATP Binding Pyrophosphatase Activity Enzyme Binding
	Biological Process	Purine Nucleobase Metabolic Process GMP Biosynthetic Process Glutamine Metabolic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Drug Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	Protein Sumoylation
Pathways		Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs		L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AGPAT2 SUMO4	75 interactors: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GNB2L1 GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		8833	387082
HPRD ID		10927	10584
Ensembl ID		ENSG00000163655	ENSG00000177688
Uniprot IDs		A8K639 B4DUT7 P49915	Q6EEV6
PDB IDs		2VPI 2VXO
Enriched GO Terms of Interacting Partners?		CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Protein Sumoylation Phosphatidic Acid Biosynthetic Process Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Triglyceride Biosynthetic Process Triglyceride Metabolic Process Regulation Of Cytokine-mediated Signaling Pathway Neutral Lipid Metabolic Process	Protein Folding Regulation Of Cell Death Regulation Of Apoptotic Process Cellular Metabolic Process Response To Unfolded Protein Response To Stress Negative Regulation Of Cell Death 'de Novo' Protein Folding Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Toxin Transport Response To Organic Substance Nitrogen Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Metabolic Process Cellular Response To Stress Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Generation Of Precursor Metabolites And Energy Regulation Of Cellular Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Process Response To Reactive Oxygen Species Small Molecule Metabolic Process Organic Acid Metabolic Process Hydrogen Peroxide Catabolic Process Regulation Of Protein Metabolic Process Carboxylic Acid Metabolic Process Protein Refolding Endoplasmic Reticulum Unfolded Protein Response Ribonucleoside Monophosphate Biosynthetic Process Carbohydrate Biosynthetic Process Cellular Response To Organic Substance MRNA Metabolic Process Cellular Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Nucleoside Monophosphate Biosynthetic Process Gluconeogenesis Monocarboxylic Acid Metabolic Process ER-nucleus Signaling Pathway Catabolic Process Ribose Phosphate Biosynthetic Process Apoptotic Process Biosynthetic Process Cellular Response To Topologically Incorrect Protein
Tagcloud ?		accomplished adherent allowed arrays brownian circuits clues complexity distinguish granulocyte hundreds introduce kinetics label lapse micro motion movies nearly observe patterned progenitor proved robust started throughput transition wells	accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2
Tagcloud (Difference) ?		accomplished adherent allowed arrays brownian circuits clues complexity distinguish granulocyte hundreds introduce kinetics label lapse micro motion movies nearly observe patterned progenitor proved robust started throughput transition wells	accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2
Tagcloud (Intersection) ?