GMPS and AGPAT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GMPS	AGPAT2
Gene Name		guanine monphosphate synthase	1-acylglycerol-3-phosphate O-acyltransferase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	GMP Synthase Activity GMP Synthase (glutamine-hydrolyzing) Activity ATP Binding Pyrophosphatase Activity Enzyme Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity
	Biological Process	Purine Nucleobase Metabolic Process GMP Biosynthetic Process Glutamine Metabolic Process Purine Nucleobase Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Drug Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process	Positive Regulation Of Cytokine Production Positive Regulation Of Cytokine-mediated Signaling Pathway Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Epidermis Development CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways		Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides	Synthesis of PA Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs		L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AGPAT2 SUMO4	6 interactors: ABCG8 ANKRD28 GMPS PHF11 PHRF1 SLC23A2
Entrez ID		8833	10555
HPRD ID		10927	04373
Ensembl ID		ENSG00000163655	ENSG00000169692
Uniprot IDs		A8K639 B4DUT7 P49915	O15120
PDB IDs		2VPI 2VXO
Enriched GO Terms of Interacting Partners?		CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Protein Sumoylation Phosphatidic Acid Biosynthetic Process Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Triglyceride Biosynthetic Process Triglyceride Metabolic Process Regulation Of Cytokine-mediated Signaling Pathway Neutral Lipid Metabolic Process	Negative Regulation Of Intestinal Phytosterol Absorption Negative Regulation Of Intestinal Cholesterol Absorption Transepithelial L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Transport GMP Biosynthetic Process Nucleobase Transport Intestinal Cholesterol Absorption GMP Metabolic Process Regulation Of Intestinal Cholesterol Absorption Negative Regulation Of Cholesterol Transport Lipid Digestion L-ascorbic Acid Metabolic Process Transepithelial Transport Purine Nucleobase Biosynthetic Process Organic Anion Transport Vitamin Transmembrane Transport Response To Drug Intestinal Absorption Negative Regulation Of Lipid Transport Nucleobase-containing Compound Metabolic Process Cholesterol Efflux Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Anion Transport Glutamine Metabolic Process Regulation Of Cholesterol Transport Small Molecule Metabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleobase Metabolic Process Vitamin Transport Excretion Nitrogen Compound Metabolic Process Carbohydrate Transmembrane Transport Pigment Biosynthetic Process Sterol Transport Cholesterol Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Carboxylic Acid Metabolic Process Water-soluble Vitamin Metabolic Process
Tagcloud ?		accomplished adherent allowed arrays brownian circuits clues complexity distinguish granulocyte hundreds introduce kinetics label lapse micro motion movies nearly observe patterned progenitor proved robust started throughput transition wells	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		accomplished adherent allowed arrays brownian circuits clues complexity distinguish granulocyte hundreds introduce kinetics label lapse micro motion movies nearly observe patterned progenitor proved robust started throughput transition wells	abhd5 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?