CD84 and SH2D1B

Number of citations of the paper that reports this interaction (PMID 11689425)
15

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		CD84	SH2D1B
Gene Name		CD84 molecule	SH2 domain containing 1B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Intracellular
	Molecular Function	Receptor Activity Protein Binding	Protein Binding Protein Binding, Bridging
	Biological Process	Defense Response Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Blood Coagulation Leukocyte Migration	Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Innate Immune Response
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Response to anti-TNF treatment in rheumatoid arthritis ( 23555300)
Protein-Protein Interactions		2 interactors: SH2D1A SH2D1B	8 interactors: APP CD244 CD84 ERBB2 LY9 PRDX1 SLAMF1 TRIM54
Entrez ID		8832	117157
HPRD ID		05151	12248
Ensembl ID		ENSG00000066294	ENSG00000198574
Uniprot IDs		Q9UIB8	O14796
PDB IDs		2PKD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Cytotoxicity Immune Response Regulation Of Immune System Process Cellular Defense Response Positive Regulation Of Leukocyte Mediated Cytotoxicity Immune System Process Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Leukocyte Activation Involved In Immune Response Humoral Immune Response	Immune System Process Wound Healing Response To Wounding Neuromuscular Junction Development Blood Coagulation Hemostasis Locomotion Defense Response Synaptic Growth At Neuromuscular Junction Regulation Of Body Fluid Levels Movement Of Cell Or Subcellular Component Collateral Sprouting In Absence Of Injury Negative Regulation Of Immature T Cell Proliferation In Thymus Synapse Organization Regulation Of Microtubule-based Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Innate Immune Response Axon Choice Point Recognition Response To Stress Leukocyte Migration Negative Regulation Of T Cell Differentiation In Thymus Neuron Remodeling Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Translation Positive Regulation Of Transcription From RNA Polymerase I Promoter
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