CD84

Description		CD84 molecule
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Autophagy Defense Response Immune Response Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Interleukin-18 Production Negative Regulation Of Mast Cell Activation T Cell Activation Negative Regulation Of Mast Cell Degranulation Innate Immune Response Regulation Of Store-operated Calcium Entry
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Response to anti-TNF therapy in rheumatoid arthritis ( 23555300)
Novel Interacting Genes		1 novel interacting genes: ATP1B1
Interacting Genes		2 interacting genes: SH2D1A SH2D1B
Entrez ID		8832
HPRD ID		05151
Ensembl ID		ENSG00000066294
Uniprot IDs		Q9UIB8
PDB IDs		2PKD
Enriched GO Terms of Interacting Partners?		Protein-macromolecule Adaptor Activity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Immunity Innate Immune Response Defense Response To Other Organism Defense Response To Symbiont Positive Regulation Of Lymphocyte Mediated Immunity Response To Other Organism Immune Response Defense Response Response To External Biotic Stimulus Protein Transport Into Plasma Membrane Raft Regulation Of Lymphocyte Mediated Immunity Protein Transport Into Membrane Raft Positive Regulation Of Immune Effector Process Positive Regulation Of Potassium Ion Import Across Plasma Membrane Protein Localization To Plasma Membrane Raft Adaptive Immune Response Positive Regulation Of Innate Immune Response Regulation Of Potassium Ion Import P-type Sodium:potassium-exchanging Transporter Activity Immune System Process Positive Regulation Of Sodium Ion Export Across Plasma Membrane Protein Localization To Membrane Raft Immune Effector Process Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Transporter Activator Activity Sodium:potassium-exchanging ATPase Complex Regulation Of Innate Immune Response Positive Regulation Of Defense Response Relaxation Of Cardiac Muscle Sodium Ion Export Across Plasma Membrane Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Sodium Ion Transmembrane Transport Intracellular Potassium Ion Homeostasis Leukocyte Activation Relaxation Of Muscle Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Cell Communication By Electrical Coupling Cell Communication Involved In Cardiac Conduction Intracellular Sodium Ion Homeostasis Positive Regulation Of Potassium Ion Transmembrane Transport Cell Communication MHC Class II Protein Complex Binding Positive Regulation Of Immune Response Cell Activation ATPase Activator Activity Membrane Repolarization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
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