SIGLEC5 and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SIGLEC5	TRIP13
Description		sialic acid binding Ig like lectin 5	thyroid hormone receptor interactor 13
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Cell Adhesion	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Addison's disease ( 33574239) Aggressive periodontitis ( 28449029) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Leprosy ( 25642632) Lymphocyte count ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Periodontitis ( 30218097) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 33272962)	Pancreatic cancer ( 25086665)
Interacting Genes		5 interacting genes: LGALS3BP NAPB SLC7A8 TRIP13 VAC14	113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655
Entrez ID		8778	9319
HPRD ID		05011	05145
Ensembl ID		ENSG00000268500	ENSG00000071539
Uniprot IDs		O15389	Q15645
PDB IDs		2ZG1 2ZG2 2ZG3	5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?		Female Meiosis I Meiotic Recombination Checkpoint Signaling Meiotic Cell Cycle Checkpoint Signaling L-alanine Transport Tryptophan Transport Proline Transmembrane Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport PAS Complex Presynaptic Endosome Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Negative Regulation Of Meiotic Nuclear Division Branched-chain Amino Acid Transport Organic Cation Transmembrane Transporter Activity Aromatic Amino Acid Transport L-leucine Transport Thyroid Hormone Transport Regulation Of Synaptic Vesicle Priming Glycine Transport Platelet Dense Granule Lumen L-amino Acid Transmembrane Transporter Activity Alanine Transport Negative Regulation Of Meiotic Cell Cycle Female Meiotic Nuclear Division Neutral L-amino Acid Transmembrane Transporter Activity Synaptonemal Complex Assembly Scavenger Receptor Activity Oocyte Maturation Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Synaptonemal Complex Organization Male Meiosis I Regulation Of Meiotic Nuclear Division Reciprocal Meiotic Recombination Microvillus Membrane Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Peptide Antigen Binding Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament
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