SIGLEC5

Description		sialic acid binding Ig like lectin 5
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GO Annotations	Cellular Component	Plasma Membrane Membrane Secretory Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation
Drugs
Diseases
GWAS		Addison's disease ( 33574239) Aggressive periodontitis ( 28449029) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Leprosy ( 25642632) Lymphocyte count ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Periodontitis ( 30218097) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 33272962)
Interacting Genes		5 interacting genes: LGALS3BP NAPB SLC7A8 TRIP13 VAC14
Entrez ID		8778
HPRD ID		05011
Ensembl ID		ENSG00000268500
Uniprot IDs		O15389
PDB IDs		2ZG1 2ZG2 2ZG3
Enriched GO Terms of Interacting Partners?		Female Meiosis I Meiotic Recombination Checkpoint Signaling Meiotic Cell Cycle Checkpoint Signaling L-alanine Transport Tryptophan Transport Proline Transmembrane Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport PAS Complex Presynaptic Endosome Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Negative Regulation Of Meiotic Nuclear Division Branched-chain Amino Acid Transport Organic Cation Transmembrane Transporter Activity Aromatic Amino Acid Transport L-leucine Transport Thyroid Hormone Transport Regulation Of Synaptic Vesicle Priming Glycine Transport Platelet Dense Granule Lumen L-amino Acid Transmembrane Transporter Activity Alanine Transport Negative Regulation Of Meiotic Cell Cycle Female Meiotic Nuclear Division Neutral L-amino Acid Transmembrane Transporter Activity Synaptonemal Complex Assembly Scavenger Receptor Activity Oocyte Maturation Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Synaptonemal Complex Organization Male Meiosis I Regulation Of Meiotic Nuclear Division Reciprocal Meiotic Recombination Microvillus Membrane Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Peptide Antigen Binding Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
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