SRSF9 and FUS

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SRSF9	FUS
Gene Name		serine/arginine-rich splicing factor 9	FUS RNA binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding DNA Binding RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP C1QBP DUSP11 FUS HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMY1A1 SAFB SRPK2 TRA2B YBX1	39 interactors: ATXN1L CTNNB1 ESRRA EWSR1 GRIN1 GRIN2D IL7R ILF3 KHDRBS3 MAX MDH1 NKD2 NUPR1 PA2G4 POLR2A PRMT1 PSMB7 PTBP1 RBMX RELA RXRA SAFB2 SF1 SFPQ SPI1 SRRM1 SRSF10 SRSF2 SRSF4 SRSF9 SUV39H1 TAF15 TARDBP TDRD3 THRA TNIP1 WBP4 YBX1 ZMYM2
Entrez ID		8683	2521
HPRD ID		09053	00660
Ensembl ID		ENSG00000111786	ENSG00000089280
Uniprot IDs		Q13242	P35637 Q13344 Q6IBQ5
PDB IDs			2LA6 2LCW 4FDD 4FQ3
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Ribonucleoprotein Complex Assembly Cellular Metabolic Process Nuclear Speck Organization Response To Injury Involved In Regulation Of Muscle Adaptation Spliceosomal Complex Assembly Response To Wounding Platelet Degranulation Ribonucleoprotein Complex Biogenesis Interleukin-7-mediated Signaling Pathway Positive Regulation Of Trophoblast Cell Migration Synaptic Growth At Neuromuscular Junction Negative Regulation Of MDA-5 Signaling Pathway Transcription, DNA-templated Regulation Of Protein Processing Collateral Sprouting In Absence Of Injury Polynucleotide 5' Dephosphorylation Blood Coagulation RNA Biosynthetic Process Hemostasis Positive Regulation Of Metabolic Process Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition CRD-mediated MRNA Stabilization Negative Regulation Of T Cell Mediated Cytotoxicity Growth Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Mitochondrial Translation See more	Gene Expression Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process RNA Splicing Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process MRNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Splicing Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Splicing Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription, DNA-templated MRNA Export From Nucleus RNA Export From Nucleus Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter See more
Tagcloud ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 oaz1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 stimuli tardbp thoughts top tsp	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Difference) ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 oaz1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 stimuli tardbp thoughts top tsp	antitrypsin chn chondrosarcoma desmin desmoplastic ectomesenchymoma etv1 ews extraskeletal fkhr fli1 hhf35 liposarcoma mic2 myod1 myxoid p22 pax pnet q12 q14 q22 q24 q35 ssx1 stt stts syt tec witnessed
Tagcloud (Intersection) ?