SRSF9 and C1QBP

Number of citations of the paper that reports this interaction (PMID 10022843)
38

Data Source:
HPRD (in vitro)

		SRSF9	C1QBP
Gene Name		serine/arginine-rich splicing factor 9	complement component 1, q subcomponent binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus	Extracellular Space Nucleus Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane Cell Surface Membrane
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Complement Component C1q Binding Transcription Corepressor Activity MRNA Binding Protein Kinase C Binding Protein Binding Hyaluronic Acid Binding Transcription Factor Binding Kininogen Binding Adrenergic Receptor Binding Mitochondrial Ribosome Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated MRNA Processing Apoptotic Process Immune Response Complement Activation, Classical Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway RNA Splicing Phosphatidylinositol 3-kinase Signaling Viral Process Regulation Of Complement Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Mature Ribosome Assembly Positive Regulation Of Apoptotic Process Innate Immune Response Positive Regulation Of Cell Adhesion Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Defense Response To Virus Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Translation Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Trophoblast Cell Migration Positive Regulation Of Dendritic Cell Chemotaxis
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Intrinsic Pathway Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP C1QBP DUSP11 FUS HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMY1A1 SAFB SRPK2 TRA2B YBX1	24 interactors: C1QA CEBPA COIL EXOSC6 GAB1 GABRB1 HABP4 HNRNPD HRK MAPK1 MAPK3 MMP14 NFKBIE NFYB PRKCA PRKCD PRKCZ PRKD1 PRRC2A SRSF1 SRSF9 TOP3B YWHAB YWHAG
Entrez ID		8683	708
HPRD ID		09053	03168
Ensembl ID		ENSG00000111786	ENSG00000108561
Uniprot IDs		Q13242	Q07021
PDB IDs			1P32 3RPX
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Ribonucleoprotein Complex Assembly Cellular Metabolic Process Nuclear Speck Organization Response To Injury Involved In Regulation Of Muscle Adaptation Spliceosomal Complex Assembly Response To Wounding Platelet Degranulation Ribonucleoprotein Complex Biogenesis Interleukin-7-mediated Signaling Pathway Positive Regulation Of Trophoblast Cell Migration Synaptic Growth At Neuromuscular Junction Negative Regulation Of MDA-5 Signaling Pathway Transcription, DNA-templated Regulation Of Protein Processing Collateral Sprouting In Absence Of Injury Polynucleotide 5' Dephosphorylation Blood Coagulation RNA Biosynthetic Process Hemostasis Positive Regulation Of Metabolic Process Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition CRD-mediated MRNA Stabilization Negative Regulation Of T Cell Mediated Cytotoxicity Growth Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Mitochondrial Translation	Vascular Endothelial Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cellular Protein Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Cellular Response To Insulin Stimulus Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Neurotrophin Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Metabolic Process Defense Response Cellular Response To Organonitrogen Compound Regulation Of Protein Kinase Activity Response To Insulin Insulin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Cellular Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Regulation Of Kinase Activity Cellular Response To Peptide Innate Immune Response Response To Organonitrogen Compound Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of MAPK Cascade Immune Response Regulation Of Phosphorylation Response To Hormone Regulation Of Cellular Amino Acid Metabolic Process Apoptotic Process Cell Activation Blood Coagulation Programmed Cell Death Hemostasis Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Response To Peptide Hormone Cell Death Death Regulation Of Phosphorus Metabolic Process
Tagcloud ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 oaz1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 stimuli tardbp thoughts top tsp	133a a2m affymetrix afzelii borrelia burgdorferii burgeforii c1s cd46 cd59 cfb cfh complement cultivation defence differentiates diploid fhl1 garinii genospecies hgu launch penetrating sensu spirochaete spirochaetes stricto transcriptomes vsig4
Tagcloud (Difference) ?		anticipate cbx3 cyp2a6 disc downloaded fntb gse1648 hyper hypo inferred intervertebral iso ivd normalization npm1 oaz1 omnibus osmotic pair physicochemical physiologic prpf8 rps5 slc25a3 stimuli tardbp thoughts top tsp	133a a2m affymetrix afzelii borrelia burgdorferii burgeforii c1s cd46 cd59 cfb cfh complement cultivation defence differentiates diploid fhl1 garinii genospecies hgu launch penetrating sensu spirochaete spirochaetes stricto transcriptomes vsig4
Tagcloud (Intersection) ?