SRSF9 and C1QBP

Number of citations of the paper that reports this interaction (PubMedID 10022843)
53

Data Source:
HPRD (in vitro)

		SRSF9	C1QBP
Description		serine and arginine rich splicing factor 9	complement C1q binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Extracellular Region Extracellular Space Nucleus Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane Cell Surface Membrane Presynaptic Active Zone Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding	Complement Component C1q Complex Binding Transcription Corepressor Activity MRNA Binding Enzyme Inhibitor Activity Protein Kinase C Binding Protein Binding Hyaluronic Acid Binding Transcription Factor Binding Kininogen Binding Adrenergic Receptor Binding Deoxyribonuclease Inhibitor Activity C5-methylcytidine-containing RNA Reader Activity Mitochondrial Ribosome Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition MRNA Processing RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Homologous Recombination Mitochondrial RNA Catabolic Process Adaptive Immune Response Immune System Process MRNA Processing Apoptotic Process Immune Response Complement Activation, Classical Pathway DNA Damage Response RNA Splicing Regulation Of Complement Activation Negative Regulation Of Type II Interferon Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Ribosome Biogenesis Cytosolic Ribosome Assembly Positive Regulation Of Apoptotic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Innate Immune Response Positive Regulation Of Cell Adhesion Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Defense Response To Virus Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Mitochondrial Translation Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Dendritic Cell Chemotaxis
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination	Apoptotic factor-mediated response Intrinsic Pathway of Fibrin Clot Formation RHOA GTPase cycle RHOC GTPase cycle Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
Drugs			Hyaluronic acid Copper
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Menopause (age at onset) ( 26414677) Reticulocyte fraction of red cells ( 32888494)	Rheumatoid arthritis ( 24390342 30423114)
Interacting Genes		18 interacting genes: APP C1QBP DUSP11 FUS H19 HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMY1A1 RNPS1 SAFB SHANK3 SRPK2 TRA2B YBX1	105 interacting genes: C1QA CDK13 CEBPA COIL DUX4 EXOSC6 FOXP1 GAB1 GABRB1 HABP4 HMGB1 HMGB2 HNRNPD HRK KLF1 MAPK1 MAPK3 MBD1 MBD2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MMP14 NFKBIE NFYB PRKCA PRKCD PRKCZ PRKD1 PRRC2A SHANK3 SRSF1 SRSF9 TOP3B ULK1 YWHAB YWHAG
Entrez ID		8683	708
HPRD ID		09053	03168
Ensembl ID		ENSG00000111786	ENSG00000108561
Uniprot IDs		Q13242	Q07021
PDB IDs			1P32 3RPX 6SZW 7TE3
Enriched GO Terms of Interacting Partners?		RNA Splicing Regulation Of RNA Splicing RNA Processing MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Binding RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Binding Positive Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process C5-methylcytidine-containing RNA Reader Activity MRNA Binding Positive Regulation Of RNA Splicing Nucleic Acid Metabolic Process Macromolecule Metabolic Process Apolipoprotein Binding Nuclear Body Organization Nucleobase-containing Compound Metabolic Process Sarcoplasm Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Biosynthetic Process Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of RNA Splicing Regulation Of Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression Amyloid Fibril Formation Regulation Of DNA Recombination Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Primary Metabolic Process Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Adrenergic Receptor Binding Positive Regulation Of Sphingolipid Mediated Signaling Pathway High-density Lipoprotein Particle Receptor Activity High Density Lipoprotein Particle Mediated Signaling Response To Injury Involved In Regulation Of Muscle Adaptation	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Regulation Of Macromolecule Metabolic Process Regulation Of Angiogenesis Positive Regulation Of MRNA Catabolic Process Regulation Of Vasculature Development Regulation Of MRNA Stability Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Angiogenesis Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Vasculature Development Regulation Of Cell Migration Regulation Of Cell Motility Negative Regulation Of Developmental Process Regulation Of Locomotion Regulation Of MRNA Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Signal Transduction Regulation Of Developmental Process Negative Regulation Of Blood Vessel Endothelial Cell Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?