SRSF9 and SAFB

Number of citations of the paper that reports this interaction (PubMedID 11118435)
0

Data Source:
HPRD (in vivo)

		SRSF9	SAFB
Description		serine and arginine rich splicing factor 9	scaffold attachment factor B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Nucleus Nucleoplasm Midbody
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition MRNA Processing RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing Regulation Of Androgen Receptor Signaling Pathway
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Menopause (age at onset) ( 26414677) Reticulocyte fraction of red cells ( 32888494)	Mean reticulocyte volume ( 32888494)
Interacting Genes		18 interacting genes: APP C1QBP DUSP11 FUS H19 HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMY1A1 RNPS1 SAFB SHANK3 SRPK2 TRA2B YBX1	30 interacting genes: ABHD16A CDC37 CEBPA CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R LINC00941 MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2
Entrez ID		8683	6294
HPRD ID		09053	04205
Ensembl ID		ENSG00000111786	ENSG00000160633
Uniprot IDs		Q13242	B7Z2F6 B7ZLP5 Q15424
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing Regulation Of RNA Splicing RNA Processing MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Binding RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Binding Positive Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process C5-methylcytidine-containing RNA Reader Activity MRNA Binding Positive Regulation Of RNA Splicing Nucleic Acid Metabolic Process Macromolecule Metabolic Process Apolipoprotein Binding Nuclear Body Organization Nucleobase-containing Compound Metabolic Process Sarcoplasm Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Biosynthetic Process Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of RNA Splicing Regulation Of Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression Amyloid Fibril Formation Regulation Of DNA Recombination Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Primary Metabolic Process Positive Regulation Of Translation Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Adrenergic Receptor Binding Positive Regulation Of Sphingolipid Mediated Signaling Pathway High-density Lipoprotein Particle Receptor Activity High Density Lipoprotein Particle Mediated Signaling Response To Injury Involved In Regulation Of Muscle Adaptation	Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulatory NcRNA-mediated Gene Silencing Regulation Of Metabolic Process Regulation Of RNA Splicing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Regulation Of Gene Expression Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Regulation Of MRNA Processing Post-transcriptional Gene Silencing Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RISC Complex Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression RNA Splicing MRNA Base-pairing Post-transcriptional Repressor Activity Nucleoplasm Negative Regulation Of Metabolic Process Nucleic Acid Binding RNA Binding MRNA Metabolic Process Chromatin RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Protein Domain Specific Binding Positive Regulation Of Catabolic Process MRNA 3'-UTR Binding Chromatin Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing DNA Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of MRNA Stability Nucleus Nucleic Acid Metabolic Process ATP-dependent Chromatin Remodeler Activity
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