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FUS and SAFB2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
FUS
SAFB2
Gene Name
FUS RNA binding protein
scaffold attachment factor B2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nucleoplasm
Cytoplasm
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Nucleotide Binding
DNA Binding
RNA Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Poly(A) RNA Binding
Nucleotide Binding
DNA Binding
Protein Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
RNA Splicing
Gene Expression
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
vWF and FVIII levels (
21810271
)
Protein-Protein Interactions
39 interactors:
ATXN1L
CTNNB1
ESRRA
EWSR1
GRIN1
GRIN2D
IL7R
ILF3
KHDRBS3
MAX
MDH1
NKD2
NUPR1
PA2G4
POLR2A
PRMT1
PSMB7
PTBP1
RBMX
RELA
RXRA
SAFB2
SF1
SFPQ
SPI1
SRRM1
SRSF10
SRSF2
SRSF4
SRSF9
SUV39H1
TAF15
TARDBP
TDRD3
THRA
TNIP1
WBP4
YBX1
ZMYM2
8 interactors:
CHGB
ESR1
FNTA
FUS
GIT2
SAFB
SORBS3
ZSCAN18
Entrez ID
2521
9667
HPRD ID
00660
06424
Ensembl ID
ENSG00000089280
ENSG00000130254
Uniprot IDs
P35637
Q13344
Q6IBQ5
Q14151
PDB IDs
2LA6
2LCW
4FDD
4FQ3
Enriched GO Terms of Interacting Partners
?
Gene Expression
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Macromolecule Biosynthetic Process
RNA Splicing
Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
MRNA Processing
Transcription From RNA Polymerase II Promoter
Biosynthetic Process
MRNA Metabolic Process
Regulation Of Transcription, DNA-templated
RNA Processing
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Splicing
Positive Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of RNA Splicing
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Transcription, DNA-templated
MRNA Export From Nucleus
RNA Export From Nucleus
Positive Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Intracellular Estrogen Receptor Signaling Pathway
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Tubulin Deacetylation
Prostate Epithelial Cord Elongation
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Protein Farnesylation
Hormone Metabolic Process
Regulation Of Tubulin Deacetylation
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Positive Regulation Of Deacetylase Activity
Branch Elongation Involved In Mammary Gland Duct Branching
Antral Ovarian Follicle Growth
Neurotransmitter Receptor Metabolic Process
Protein Geranylgeranylation
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Branching Involved In Pregnancy
Regulation Of Hormone Levels
Positive Regulation Of Hydrolase Activity
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Vagina Development
Uterus Development
Protein Prenylation
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Positive Regulation Of Nitric-oxide Synthase Activity
Cellular Response To Estradiol Stimulus
Prostate Gland Growth
Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Epithelial Cell Proliferation
Female Genitalia Development
Behavioral Response To Pain
Regulation Of Signaling
Positive Regulation Of Monooxygenase Activity
Branch Elongation Of An Epithelium
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Deacetylation
Regulation Of Rhodopsin Mediated Signaling Pathway
Cellular Response To Estrogen Stimulus
RNA Metabolic Process
Growth
Tagcloud
?
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
fli1
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
Tagcloud (Difference)
?
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
fli1
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
Tagcloud (Intersection)
?