SSNA1 and GOPC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SSNA1	GOPC
Gene Name		Sjogren syndrome nuclear autoantigen 1	golgi-associated PDZ and coiled-coil motif containing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Ciliary Basal Body	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane
	Molecular Function	Identical Protein Binding	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Intraciliary Transport Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Colorectal cancer ( 23266556)
Protein-Protein Interactions		8 interactors: EHHADH GOPC LNX1 SDCBP SPAST TBC1D7 TCEANC TXN2	58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1
Entrez ID		8636	57120
HPRD ID		10251	06024
Ensembl ID		ENSG00000176101	ENSG00000047932
Uniprot IDs		O43805	Q9HD26
PDB IDs			2DC2 2LOB 4E34 4E35
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Cytoplasmic Sequestering Of CFTR Protein ER To Golgi Vesicle-mediated Transport Cytokinesis, Completion Of Separation Negative Regulation Of Cilium Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Microtubule Depolymerization Regulation Of Extracellular Vesicular Exosome Assembly Cellular Component Assembly Negative Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Component Organization Mitotic Cytokinetic Process Regulation Of Organelle Organization Protein Hexamerization Regulation Of Golgi To Plasma Membrane Protein Transport Golgi Vesicle Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Complex Assembly Substrate-dependent Cell Migration, Cell Extension Microtubule Severing Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane	Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism
Tagcloud ?		auto autoantigen axon axonopathy branching cardinal centrioles centrosomes corticospinal cytokinesis extremity hsp hsps localizing na14 outgrowth paraplegias postulate severing severs sjogren spastic spasticity spastin spatially spg1 spg4 temporally tubulation	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Difference) ?		auto autoantigen axon axonopathy branching cardinal centrioles centrosomes corticospinal cytokinesis extremity hsp hsps localizing na14 outgrowth paraplegias postulate severing severs sjogren spastic spasticity spastin spatially spg1 spg4 temporally tubulation	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Intersection) ?