GBF1

Gene Name		golgi brefeldin A resistant guanine nucleotide exchange factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Mitochondrion Peroxisome Endoplasmic Reticulum Lumen Golgi Apparatus Golgi Stack Cis-Golgi Network Trans-Golgi Network Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Organelle Organization Viral Process Vesicle-mediated Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance VxPx cargo-targeting to cilium COPI Mediated Transport Assembly of the primary cilium trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: PNPLA2 USO1 YWHAG
Entrez ID		8729
HPRD ID		04740
Ensembl ID		ENSG00000107862
Uniprot IDs		Q149P0 Q149P1 Q92538
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Docking Acylglycerol Acyl-chain Remodeling Negative Regulation Of Sequestering Of Triglyceride Vesicle Fusion With Golgi Apparatus Positive Regulation Of Triglyceride Catabolic Process Transcytosis Lipid Particle Organization Negative Regulation Of Lipid Storage Organelle Organization Triglyceride Catabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Mitotic Cell Cycle Acylglycerol Catabolic Process Positive Regulation Of Lipid Catabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Membrane Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Triglyceride Metabolic Process Intracellular Protein Transport Lipid Storage Vesicle Fusion Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Positive Regulation Of Mitochondrion Organization Cell Cycle Cellular Protein Localization Organelle Fusion Protein Transport Vesicle Docking Establishment Of Protein Localization Membrane Docking Regulation Of Mitochondrion Organization Intracellular Transport Triglyceride Metabolic Process ER To Golgi Vesicle-mediated Transport
Tagcloud ?		accumulated arf arf1 arfgef caenorhabditis cdc48 cerevisiae coat contact contacts elegans evolutionarily fractionated fzo1 gem1 gtpase initiating interacted mitochondria mitochondrial mitofusin modifying resolved saccharomyces traffic unexpected vesicular worms