GNAI1 and CD47

Number of citations of the paper that reports this interaction (PMID 11306274)
111

Data Source:
HPRD (in vivo)

		GNAI1	CD47
Gene Name		guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	CD47 molecule
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lysosomal Membrane Centrosome Heterotrimeric G-protein Complex Plasma Membrane Midbody Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Signal Transducer Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding G-protein Coupled Serotonin Receptor Binding Metal Ion Binding	Protein Binding Thrombospondin Receptor Activity
	Biological Process	Cell Cycle G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission Blood Coagulation Platelet Activation Response To Peptide Hormone Cell Division	Cell Adhesion Integrin-mediated Signaling Pathway Blood Coagulation Opsonization Positive Regulation Of Cell Proliferation Response To Bacterium Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Positive Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Leukocyte Migration
Pathways		Signaling by GPCR Integration of energy metabolism G alpha (s) signalling events Activation of GABAB receptors Signal amplification G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell ADP signalling through P2Y purinoceptor 12 GABA B receptor activation Adenylate cyclase inhibitory pathway GABA receptor activation PLC beta mediated events Opioid Signalling Regulation of insulin secretion G-protein mediated events Adrenaline,noradrenaline inhibits insulin secretion Inhibition of adenylate cyclase pathway Adenylate cyclase inhibitory pathway GPCR downstream signaling G-protein activation Platelet activation, signaling and aggregation Transmission across Chemical Synapses	Integrin cell surface interactions Signal regulatory protein (SIRP) family interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		57 interactors: ADCY5 ADRA2A CCR5 CD47 CNR1 CRHR1 CXCR4 DRD3 EPOR ESR1 FFAR1 GNAO1 GNB2 GNB4 GPR1 GPR143 GPSM1 GPSM2 GPSM3 HRH4 HTR2A IGF1R KLHL3 MTNR1A MTNR1B NGB NUCB1 NUMA1 OPRD1 OPRM1 PDE6D PTPRU RANGAP1 RASD1 RGS10 RGS12 RGS14 RGS16 RGS17 RGS18 RGS19 RGS20 RGS4 RGS7 RIC8A S1PR1 S1PR2 S1PR3 S1PR4 S1PR5 SSTR2 SSTR3 STRN THAP7 TSHR VIPR1 WASF1	12 interactors: BNIP3 EPB42 FAS GNAI1 ITGAV P2RY2 PTK2 RHAG SIRPA SYNE4 THBS1 UBQLN1
Entrez ID		2770	961
HPRD ID		00756	03017
Ensembl ID		ENSG00000127955	ENSG00000196776
Uniprot IDs		P63096	Q08722
PDB IDs		1KJY 1Y3A 2G83 2GTP 2IK8 2OM2 2PZ3 2XNS 3ONW 3QE0 3QI2 3UMR 3UMS 4G5Q	2JJS 2JJT 2VSC 4KJY
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Signaling Cell Communication Regulation Of Catalytic Activity Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Cellular Response To Stimulus Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Response To Stimulus Regulation Of Signaling Positive Regulation Of Hydrolase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Sphingosine-1-phosphate Signaling Pathway Regulation Of Cellular Process Chemical Homeostasis Cell-cell Signaling Cytosolic Calcium Ion Homeostasis Positive Regulation Of GTPase Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of GTPase Activity Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Synaptic Transmission Negative Regulation Of Signaling Behavior Cellular Metal Ion Homeostasis Neuropeptide Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Cellular Cation Homeostasis Ion Homeostasis Cellular Ion Homeostasis Homeostatic Process Metal Ion Homeostasis Negative Regulation Of Signal Transduction Cellular Chemical Homeostasis Locomotory Behavior Response To Ammonium Ion Negative Regulation Of Ion Transport Response To Cocaine Regulation Of Cell Proliferation Neurological System Process	Blood Coagulation Hemostasis Immune System Process Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cellular Response To Oxygen Levels Regulation Of Apoptotic Process Cellular Response To Inorganic Substance Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Stress Negative Regulation Of Lipid Transport Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Cell Death Death Platelet Activation Response To Hyperoxia Apoptotic Cell Clearance Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Mechanical Stimulus Regulation Of Cellular Component Organization Erythrocyte Development Homeostasis Of Number Of Cells Peptide Cross-linking Spleen Development Regulation Of Focal Adhesion Assembly Phagocytosis Cell Activation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Neuron Apoptotic Process Response To Hypoxia Regulation Of Cell Junction Assembly Cell Differentiation Neuron Death Angiogenesis Response To Metal Ion Positive Regulation Of Cell Migration Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Positive Regulation Of Cell Motility Cell Migration Apoptotic Signaling Pathway
Tagcloud ?		alkenes azotic constructions gnao1 heterocycle hm hms htr1b htr2a htr2b htr4 htr6 htr7 kpnb1 pharmacopeia prkaca prkca prkcb prkcd prkce prkcg prkd1 propertied pubchem rock2 rps6ka1 rps6ka3 tlr8 tradition	1p34 ancestral asymmetry bilayer connecting deduced duffy ee glycophorin glycoproteins glycosylated helices hydrophilic leaflets loops lw multimeric occasions phospholipid primates reside rh rh50 rhce rhd rhnull specificities suffer topology
Tagcloud (Difference) ?		alkenes azotic constructions gnao1 heterocycle hm hms htr1b htr2a htr2b htr4 htr6 htr7 kpnb1 pharmacopeia prkaca prkca prkcb prkcd prkce prkcg prkd1 propertied pubchem rock2 rps6ka1 rps6ka3 tlr8 tradition	1p34 ancestral asymmetry bilayer connecting deduced duffy ee glycophorin glycoproteins glycosylated helices hydrophilic leaflets loops lw multimeric occasions phospholipid primates reside rh rh50 rhce rhd rhnull specificities suffer topology
Tagcloud (Intersection) ?