AGPS and GNPAT

Number of citations: 0 (PubMedID 10215861)
Data Source: HPRD (in vitro, in vivo)

		AGPS	GNPAT
Name		alkylglycerone phosphate synthase	glyceronephosphate O-acyltransferase
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Cell Junction
	Molecular Function	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding	Catalytic Activity O-acyltransferase Activity Glycerone-phosphate O-acyltransferase Activity Transferase Activity Acyltransferase Activity
	Biological Process	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process	Lipid Metabolic Process Glycerophospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Synapse Assembly Ether Lipid Biosynthetic Process Cerebellum Morphogenesis Paranodal Junction Assembly Myelination Membrane Organization
Pathways		Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Synthesis of PA Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)	Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Height ( 28552196 )	No GWAS studies recorded
Novel Interactors		12 novel interactors: BLVRA BOLL CHRND CS FKBP7 GORASP2 KCNH7 KEL LST1 NFIA PDE11A TSFM	None recorded
Interacting Genes		2 interacting genes: GNPAT GORASP1	6 interacting genes: AGPS GPR3 HSPB1 PEX5 RAB35 VDR
Entrez ID		8540	8443
HPRD ID		04337	04120
Ensembl ID		ENSG00000018510	ENSG00000116906
Uniprot IDs		B7Z3Q4 O00116	O15228
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Peroxisome Matrix Targeting Signal-1 Binding Peroxisomal Matrix Peroxisome Targeting Sequence Binding Peroxisomal Membrane Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Phosphate Transmembrane Transport Calcitriol Binding Nuclear Receptor-mediated Bile Acid Signaling Pathway Apoptotic Process Involved In Mammary Gland Involution Vitamin D Response Element Binding Bile Acid Nuclear Receptor Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Mammary Gland Branching Involved In Pregnancy Vitamin D Receptor Signaling Pathway Lithocholic Acid Binding Alkylglycerone-phosphate Synthase Activity Regulation Of Protein Kinase C Signaling Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Positive Regulation Of Vitamin D Receptor Signaling Pathway Response To Bile Acid Vitamin D Binding Positive Regulation Of Apoptotic Process Involved In Morphogenesis Sphingosine-1-phosphate Receptor Activity Anterograde Axonal Protein Transport Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Positive Regulation Of Apoptotic Process Involved In Development Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Phosphate Transport Plasma Membrane To Endosome Transport Cellular Response To Growth Factor Stimulus Positive Regulation Of Endothelial Cell Chemotaxis Protein Transport Protein Transport Along Microtubule Response To Growth Factor Contractile Muscle Fiber Protein Unfolding Protein Import Into Peroxisome Matrix Phosphate Ion Transmembrane Transport Ether Lipid Biosynthetic Process Protein Localization To Endosome Cell Projection Membrane