AGPS and CS

		AGPS	CS
Description		alkylglycerone phosphate synthase	citrate synthase
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Nucleus Mitochondrion Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding	RNA Binding Transferase Activity Citrate Synthase Activity Identical Protein Binding Acyltransferase Activity, Acyl Groups Converted Into Alkyl On Transfer
	Biological Process	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process
Pathways		Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Mitochondrial protein import Citric acid cycle (TCA cycle) Mitochondrial protein degradation Maturation of TCA enzymes and regulation of TCA cycle
Drugs			Trifluoroacetonyl coenzyme A Coenzyme A Oxaloacetate Ion alpha-Fluoro-carboxymethyldethia coenzyme A complex D-Malic acid Nitromethyldethia coenzyme A Citric acid
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Height ( 28552196)	Height ( 23456168 31562340 34270706) Inflammatory skin disease ( 25574825) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: GNPAT GORASP1	8 interacting genes: CRYAA CRYAB DYNLL1 HSD17B10 HSPB1 LCOR LINC01554 MDH2
Entrez ID		8540	1431
HPRD ID		04337	00349
Ensembl ID		ENSG00000018510	ENSG00000062485
Uniprot IDs		B7Z3Q4 O00116	O75390
PDB IDs			5UZP 5UZQ 5UZR
Enriched GO Terms of Interacting Partners?			Protein Refolding Tubulin Complex Assembly Response To Heat Unfolded Protein Binding Contractile Muscle Fiber Structural Constituent Of Eye Lens Apoptotic Process Involved In Morphogenesis Response To Temperature Stimulus Apoptotic Process Involved In Development Protein Folding Lens Development In Camera-type Eye Regulation Of Intracellular Transport Negative Regulation Of Intracellular Transport Microtubule-based Process Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Negative Regulation Of Protein Kinase C Signaling Axon Cytoplasm L-malate Dehydrogenase (NADP+) Activity Alkylglycerone-phosphate Synthase Activity Mitochondrion Camera-type Eye Development Identical Protein Binding 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Brexanolone Metabolic Process Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Response To Hydrogen Peroxide Response To Estradiol Mitochondrial Ribonuclease P Complex Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing Mitochondrial TRNA Methylation Protein Kinase C Inhibitor Activity L-malate Dehydrogenase (NAD+) Activity Malate Dehydrogenase Activity Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Eye Development Regulation Of Cellular Localization Z Disc Mitochondrial RNA 5'-end Processing Isoleucine Metabolic Process L-isoleucine Catabolic Process Regulation Of Protein Kinase C Signaling Response To Reactive Oxygen Species TRNA Methyltransferase Complex
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