AGPS and KEL

		AGPS	KEL
Description		alkylglycerone phosphate synthase	Kell metallo-endopeptidase (Kell blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane	Nucleoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane
	Molecular Function	Catalytic Activity Protein Binding Alkylglycerone-phosphate Synthase Activity Transferase Activity Flavin Adenine Dinucleotide Binding FAD Binding	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Lipid Biosynthetic Process Ether Lipid Biosynthetic Process	Proteolysis Intracellular Calcium Ion Homeostasis Regulation Of Cell Size Intracellular Magnesium Ion Homeostasis Protein Processing Regulation Of Axon Diameter Vasoconstriction Myelination Skeletal Muscle Fiber Development Establishment Of Localization In Cell Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways		Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Peptide ligand-binding receptors
Drugs			Phosphoramidon
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Height ( 28552196)	Alcoholic chronic pancreatitis ( 28754779) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494)
Interacting Genes		2 interacting genes: GNPAT GORASP1	12 interacting genes: ADIPOQ C3orf52 C5 CLDN19 EDN1 EDN2 EDN3 EWSR1 PM20D2 TUBA1A UBC XK
Entrez ID		8540	3792
HPRD ID		04337	00194
Ensembl ID		ENSG00000018510	ENSG00000197993
Uniprot IDs		B7Z3Q4 O00116	A0A077QP03 P23276
PDB IDs
Enriched GO Terms of Interacting Partners?			Endothelin B Receptor Binding Vein Smooth Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Endothelin Artery Smooth Muscle Contraction Tonic Smooth Muscle Contraction Vascular Associated Smooth Muscle Contraction Positive Regulation Of Heart Rate Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Hormone Activity Positive Regulation Of Smooth Muscle Contraction Vasoconstriction Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Heart Contraction Leukocyte Chemotaxis Regulation Of Systemic Arterial Blood Pressure Axon Extension Regulation Of Blood Pressure Positive Regulation Of Muscle Contraction Intracellular Magnesium Ion Homeostasis Neutrophil Chemotaxis Smooth Muscle Contraction Intracellular Calcium Ion Homeostasis Regulation Of Smooth Muscle Contraction Cell Chemotaxis Regulation Of Chemotaxis Regulation Of Vasoconstriction Neutrophil Migration Positive Regulation Of Prostaglandin Biosynthetic Process Calcium Ion Homeostasis Regulation Of Leukocyte Migration Leukocyte Migration Granulocyte Chemotaxis Positive Regulation Of Unsaturated Fatty Acid Biosynthetic Process Neuron Projection Extension Endothelin Receptor Signaling Pathway Regulation Of Prostaglandin Biosynthetic Process Magnesium Ion Homeostasis Granulocyte Migration Positive Regulation Of Leukocyte Chemotaxis Regulation Of Fatty Acid Metabolic Process Regulation Of Cell Migration Regulation Of Heart Rate Regulation Of Cell Motility Regulation Of Locomotion Chemotaxis Developmental Cell Growth Response To Tumor Necrosis Factor Regulation Of Ketone Metabolic Process Myeloid Leukocyte Migration Locomotion
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