FAM114A2 and MIEF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM114A2	MIEF2
Description		family with sequence similarity 114 member A2	mitochondrial elongation factor 2
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding Purine Nucleotide Binding	Protein Binding
	Biological Process		Mitochondrion Organization Mitochondrial Fusion Regulation Of Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways		Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 28957414 32888494)	Change in neurofilament light levels ( 31295725)
Interacting Genes		11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA	30 interacting genes: AGTRAP ARFIP2 ARL6IP1 ATP5PF CIDEA DNM1L FAM114A2 FAM25A FAM25C FAM25G FKBP7 GSG1 HSD17B13 LIME1 MDK NCALD NCS1 PRB2 PSMF1 RABAC1 REEP6 RHBDD2 SFT2D1 SYP TMEM239 UBQLN1 UBQLN2 UBQLN4 YIF1A ZNF628
Entrez ID		10827	125170
HPRD ID		12831	18074
Ensembl ID		ENSG00000055147	ENSG00000177427
Uniprot IDs		A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5	Q96C03
PDB IDs			5WP9
Enriched GO Terms of Interacting Partners?		Autophagosome Membrane Regulation Of Amyloid-beta Clearance Cytoplasmic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Membrane Negative Regulation Of Establishment Of Blood-brain Barrier Mitochondrial MRNA Processing Protein Localization To Vacuolar Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Apparatus Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Autophagy Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Positive Regulation Of Membrane Tubulation	Endoplasmic Reticulum Polyubiquitin Modification-dependent Protein Binding Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Organization Regulation Of Proteasomal Protein Catabolic Process Endoplasmic Reticulum Membrane Regulation Of Macroautophagy Autophagosome Positive Regulation Of ERAD Pathway GTP-dependent Protein Binding ERAD Pathway
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