FAM114A2 and PILRA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM114A2	PILRA
Description		family with sequence similarity 114 member A2	paired immunoglobin like type 2 receptor alpha
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Purine Nucleotide Binding	Protein Binding MHC Class I Protein Binding
	Biological Process		Signal Transduction
Pathways		Signaling by BRAF and RAF1 fusions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 28957414 32888494)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red cell distribution width ( 32888494) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA	10 interacting genes: DNPH1 FAM114A2 FCAR PAICS PFDN5 PTPN11 PTPN6 SORBS1 TOM1 UROD
Entrez ID		10827	29992
HPRD ID		12831	05631
Ensembl ID		ENSG00000055147	ENSG00000085514
Uniprot IDs		A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5	Q9UKJ1
PDB IDs			3WUZ 3WV0 4NFB 5XO2 5XOF
Enriched GO Terms of Interacting Partners?		Autophagosome Membrane Regulation Of Amyloid-beta Clearance Cytoplasmic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Membrane Negative Regulation Of Establishment Of Blood-brain Barrier Mitochondrial MRNA Processing Protein Localization To Vacuolar Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Apparatus Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Autophagy Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Positive Regulation Of Membrane Tubulation	Neutrophil Activation Negative Regulation Of Neutrophil Activation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Myeloid Leukocyte Activation Peptidyl-tyrosine Dephosphorylation Platelet Formation Megakaryocyte Development Insulin Receptor Binding Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cellular Response To Insulin Stimulus Carboxy-lyase Activity Regulation Of Lipopolysaccharide-mediated Signaling Pathway Signaling Receptor Complex Adaptor Activity Positive Regulation Of D-glucose Import Regulation Of Type I Interferon-mediated Signaling Pathway T Cell Costimulation Positive Regulation Of D-glucose Transmembrane Transport Phosphotyrosine Residue Binding Regulation Of Cell Adhesion Mediated By Integrin IgA Receptor Activity RNA Polymerase III Assembly RNA Polymerase I Assembly Epididymis Development Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Regulation Of D-glucose Import Uroporphyrinogen Decarboxylase Activity Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity Phosphoribosylaminoimidazole Carboxylase Activity Myeloid Cell Development Regulation Of Insulin Receptor Signaling Pathway Nucleoside Monophosphate Metabolic Process Negative Regulation Of T Cell Proliferation Regulation Of D-glucose Transmembrane Transport Regulation Of Cellular Response To Insulin Stimulus Specific Granule Membrane RNA Polymerase II Core Complex Assembly Protein Dephosphorylation Intestinal Epithelial Cell Migration Myosin VI Binding 5-hydroxymethyl-dUMP N-hydrolase Activity Immune Effector Process Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Cell Adhesion Molecule Binding Protein Tyrosine Phosphatase Activity Negative Regulation Of Leukocyte Proliferation IgA Binding
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