FAM114A2 and TBRG4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM114A2	TBRG4
Description		family with sequence similarity 114 member A2	transforming growth factor beta regulator 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule
	Molecular Function	Protein Binding Purine Nucleotide Binding	RNA Binding Protein Binding
	Biological Process		Mitochondrial RNA Processing Positive Regulation Of Cell Population Proliferation MRNA Metabolic Process Regulation Of Mitochondrial MRNA Stability Regulation Of Cell Cycle Mitochondrial MRNA Processing
Pathways		Signaling by BRAF and RAF1 fusions	FASTK family proteins regulate processing and stability of mitochondrial RNAs
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 28957414 32888494)	Colorectal cancer or advanced adenoma ( 30510241) Plateletcrit ( 32888494)
Interacting Genes		11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA	24 interacting genes: AGTRAP BICD2 BSND CALCOCO2 CDR2L CMTM4 CMTM5 FAM114A2 FAM9B GPRASP2 HSD17B13 KRT27 LIME1 MAL2 MEOX2 PRB3 PTN RETREG3 SCAMP1 SFT2D1 TFIP11 TMEM239 TNFRSF10D WHR1
Entrez ID		10827	9238
HPRD ID		12831	10263
Ensembl ID		ENSG00000055147	ENSG00000136270
Uniprot IDs		A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5	B3KM73 B3KRS4 B4DU42 Q969Z0
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagosome Membrane Regulation Of Amyloid-beta Clearance Cytoplasmic Vesicle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Golgi Membrane Negative Regulation Of Establishment Of Blood-brain Barrier Mitochondrial MRNA Processing Protein Localization To Vacuolar Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Protein Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Apparatus Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Autophagy Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Positive Regulation Of Membrane Tubulation
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