IRX4

Gene Name		iroquois homeobox 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Heart Development Establishment Of Organ Orientation
Pathways
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21779381)
Protein-protein Interactions		1 interactors: RARA
Entrez ID		50805
HPRD ID		09369
Ensembl ID		ENSG00000113430
Uniprot IDs		H1AFL0 H1AFL1 P78413
PDB IDs
Enriched GO Terms of Interacting Partners?		Sertoli Cell Fate Commitment Chondroblast Differentiation Negative Regulation Of Granulocyte Differentiation Trachea Cartilage Development Outflow Tract Septum Morphogenesis Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Negative Regulation Of Translational Initiation Growth Plate Cartilage Development Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of T-helper 2 Cell Differentiation Epithelial Cell Fate Commitment Positive Regulation Of Interleukin-4 Production Retinoic Acid Receptor Signaling Pathway Regulation Of Interleukin-5 Production Response To Vitamin A Positive Regulation Of Type 2 Immune Response Endochondral Bone Growth Positive Regulation Of T-helper Cell Differentiation Glandular Epithelial Cell Development Ventricular Cardiac Muscle Cell Differentiation Cellular Response To Estrogen Stimulus Trachea Development Sertoli Cell Differentiation Negative Regulation Of Cartilage Development Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Interleukin-4 Production Apoptotic Cell Clearance Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper Cell Differentiation Cartilage Development Involved In Endochondral Bone Morphogenesis Negative Regulation Of Interferon-gamma Production Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Alpha-beta T Cell Differentiation Columnar/cuboidal Epithelial Cell Development Regulation Of Type 2 Immune Response Glandular Epithelial Cell Differentiation Regulation Of Myelination Regulation Of Phosphatidylinositol 3-kinase Activity Face Development Negative Regulation Of Myeloid Leukocyte Differentiation Cardiac Septum Morphogenesis Regulation Of Lipid Kinase Activity Embryonic Camera-type Eye Development Outflow Tract Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Prostate Gland Development Cellular Response To Retinoic Acid
Tagcloud ?		activin bmp4 cardiomyogenic discovering dish enthusiasm exploiting hesc hipsc homeodomain homogeneity hpscs implement iroquois mlc2a mlc2v myosin offering passaged pluripotent repairing robustly standardization subpopulation technically tnni3 tnnt2 troponin