DDX4 and SPSB4

Number of citations of the paper that reports this interaction (PMID 20561531)
9

Data Source:
BioGRID (unspecified method)

		DDX4	SPSB4
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	splA/ryanodine receptor domain and SOCS box containing 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Chromatoid Body Perinuclear Region Of Cytoplasm Pi-body PiP-body	Cytoplasm
	Molecular Function	Nucleic Acid Binding Helicase Activity ATP Binding	Protein Binding
	Biological Process	Male Meiosis I Multicellular Organismal Development Spermatogenesis Gene Expression Sperm Motility Regulation Of Protein Localization PiRNA Metabolic Process	Protein Ubiquitination Intracellular Signal Transduction
Pathways		PIWI-interacting RNA (piRNA) biogenesis Regulatory RNA pathways	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Stroke (ischemic) ( 23041239)
Protein-Protein Interactions		5 interactors: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4	3 interactors: DDX4 NOS2 PAWR
Entrez ID		54514	92369
HPRD ID		05593	18108
Ensembl ID		ENSG00000152670	ENSG00000175093
Uniprot IDs		Q9NQI0	Q96A44
PDB IDs			2V24
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation RNA 5'-end Processing Positive Regulation Of Meiosis I Germ-line Stem Cell Maintenance Regulation Of Meiosis I	Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Peptidyl-cysteine S-nitrosylation Interleukin-2 Biosynthetic Process Germ-line Stem Cell Maintenance Regulation Of Amyloid Precursor Protein Biosynthetic Process Interleukin-2 Production Arginine Catabolic Process Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Guanylate Cyclase Activity Spermatogenesis Male Gamete Generation Regulation Of Cellular Respiration Positive Regulation Of Glycoprotein Biosynthetic Process Nitric Oxide Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Glycoprotein Metabolic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of B Cell Proliferation Innate Immune Response In Mucosa Positive Regulation Of CGMP Biosynthetic Process Gamete Generation Positive Regulation Of CGMP Metabolic Process Organelle Organization Arginine Metabolic Process Negative Regulation Of T Cell Receptor Signaling Pathway RNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Meiotic Nuclear Division Regulation Of CGMP Biosynthetic Process Cytokine Biosynthetic Process Regulation Of Protein Localization Sexual Reproduction Regulation Of Glycoprotein Biosynthetic Process Multicellular Organismal Reproductive Process Negative Regulation Of Meiotic Cell Cycle Nitric Oxide Metabolic Process Male Meiosis I Multicellular Organism Reproduction Cytokine Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of CGMP Metabolic Process Positive Regulation Of Vasodilation Mucosal Immune Response PiRNA Metabolic Process Defense Response To Gram-negative Bacterium Negative Regulation Of B Cell Activation Superoxide Metabolic Process Regulation Of Meiosis Reproduction
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Tagcloud (Difference) ?		122c 2012cb944901 9qh azoospermia blimp1 dazl declare dppa3 envisioned fam122c funds grants hef ikbkg ipsc ipscs lin28 poi poi1 poi2 prdm1 q26 rbmx stella sublines talents vasa xq znf
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