USP32 and TRIM74

Number of citations of the paper that reports this interaction (PMID 23105109)
4

Data Source:
BioGRID (two hybrid)

		USP32	TRIM74
Gene Name		ubiquitin specific peptidase 32	tripartite motif containing 74
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Membrane	Intracellular
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Calcium Ion Binding Protein Binding	Zinc Ion Binding
	Biological Process	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: RBCK1 RNF144A TRIM46 TRIM74 ZDHHC17	11 interactors: BRCA1 LRSAM1 MGRN1 RBX1 REL RNF32 TSG101 UBE2U USP15 USP2 USP32
Entrez ID		84669	378108
HPRD ID		07612	15567
Ensembl ID			ENSG00000155428
Uniprot IDs		K7EQL6 Q8NFA0	Q86UV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Linear Polyubiquitination Negative Regulation Of Necroptotic Process Protein Ubiquitination Negative Regulation Of Necrotic Cell Death Protein Modification By Small Protein Conjugation Regulation Of Necroptotic Process Lipoprotein Transport Cellular Protein Modification Process Magnesium Ion Transport Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Necrotic Cell Death Positive Regulation Of Intracellular Signal Transduction Protein Palmitoylation Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of NF-kappaB Import Into Nucleus Cellular Protein Metabolic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Signal Transduction	Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Protein Ubiquitination Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Viral Budding Protein Deubiquitination Proteolysis Protein Modification By Small Protein Removal Protein Metabolic Process Virion Assembly Regulation Of Proteasomal Protein Catabolic Process Protein Monoubiquitination Protein Autoubiquitination Cellular Metabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Ubiquitin-dependent Endocytosis Regulation Of Protein Catabolic Process Membrane Budding Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Regulation Of Protein Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Viral Process Negative Regulation Of Gene Expression DNA Repair Negative Regulation Of Biosynthetic Process Cellular Response To Indole-3-methanol Regulation Of Proteolysis Negative Regulation Of Centriole Replication Regulation Of Extracellular Vesicular Exosome Assembly Viral Life Cycle Dosage Compensation By Inactivation Of X Chromosome
Tagcloud ?		10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified zmym4
Tagcloud (Difference) ?		10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified zmym4
Tagcloud (Intersection) ?