USP32 and TRIM46

Number of citations of the paper that reports this interaction (PMID 23105109)
4

Data Source:
BioGRID (two hybrid)

		USP32	TRIM46
Gene Name		ubiquitin specific peptidase 32	tripartite motif containing 46
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Membrane	Intracellular
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Calcium Ion Binding Protein Binding	Zinc Ion Binding
	Biological Process	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: RBCK1 RNF144A TRIM46 TRIM74 ZDHHC17	17 interactors: AK5 BRCA1 CBLC MDM4 OTUD6A RNF125 RNF7 TK1 TRIM9 TSG101 UBE2U UBE2Z UCHL5 USP1 USP15 USP2 USP32
Entrez ID		84669	80128
HPRD ID		07612	15563
Ensembl ID			ENSG00000163462
Uniprot IDs		K7EQL6 Q8NFA0	B7Z3S2 B7Z4F9 F5GYK0 Q7Z4K8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Linear Polyubiquitination Negative Regulation Of Necroptotic Process Protein Ubiquitination Negative Regulation Of Necrotic Cell Death Protein Modification By Small Protein Conjugation Regulation Of Necroptotic Process Lipoprotein Transport Cellular Protein Modification Process Magnesium Ion Transport Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Necrotic Cell Death Positive Regulation Of Intracellular Signal Transduction Protein Palmitoylation Positive Regulation Of Transcription Factor Import Into Nucleus Regulation Of NF-kappaB Import Into Nucleus Cellular Protein Metabolic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Signal Transduction	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process Catabolic Process Cellular Metabolic Process Monoubiquitinated Protein Deubiquitination Regulation Of Protein Metabolic Process Regulation Of Proteolysis Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Cellular Response To Stress DNA Metabolic Process DNA Repair Positive Regulation Of Histone H4-K20 Methylation Fetal Process Involved In Parturition DADP Biosynthetic Process Positive Regulation Of Histone H4-K16 Acetylation Regulation Of DNA Repair Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metabolic Process G0 To G1 Transition Skeletal Muscle Cell Proliferation Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Protein K27-linked Deubiquitination Negative Regulation Of SNARE Complex Assembly DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Stabilization Signal Transduction In Response To DNA Damage Regulation Of Cell Cycle Arrest Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein K33-linked Deubiquitination Protein K29-linked Deubiquitination
Tagcloud ?		10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified zmym4	a1cf activins acvr1b acvrl1 ancestry atxn2 b3gnt4 baz1b consortium excretion fractional gout gugc hlf hnf4g implicate inhbb inhibins maf nfat5 painful prkag2 replicated sfmbt1 stc1 tmem171 ube2q2 urate vegfa
Tagcloud (Difference) ?		10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified zmym4	a1cf activins acvr1b acvrl1 ancestry atxn2 b3gnt4 baz1b consortium excretion fractional gout gugc hlf hnf4g implicate inhbb inhibins maf nfat5 painful prkag2 replicated sfmbt1 stc1 tmem171 ube2q2 urate vegfa
Tagcloud (Intersection) ?