USP32 and RAB35

Number of citations of the paper that reports this interaction (PubMedID 36725886)
0

Data Source:
BioGRID (enzymatic study)

		USP32	RAB35
Description		ubiquitin specific peptidase 32	RAB35, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Endomembrane System Membrane	Endosome Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Membrane Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Cytoplasmic Vesicle Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Cysteine-type Deubiquitinase Activity Calcium Ion Binding Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Proteolysis Protein Deubiquitination Positive Regulation Of TORC1 Signaling	Mitotic Cytokinesis Intracellular Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways			TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Interleukin-6 levels ( 33517400)	Heel bone mineral density ( 30598549)
Interacting Genes		13 interacting genes: ANKRD29 DYRK1A MEOX2 MTNR1A NCK2 RAB35 RBCK1 RNF144A TRIM3 TRIM46 TRIM74 UBC ZDHHC17	11 interacting genes: APP CALCOCO2 CBR3 DENND1B GNPAT IDH3B PTPRS TBPL1 TRIM54 USP32 WDCP
Entrez ID		84669	11021
HPRD ID		07612	05010
Ensembl ID		ENSG00000170832	ENSG00000111737
Uniprot IDs		Q8NFA0	Q15286
PDB IDs			3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?		Protein Modification Process Histone H3T45 Kinase Activity Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Immune System Process Ubiquitin Protein Ligase Activity Protein Polyubiquitination Ubiquitin-protein Transferase Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Positive Regulation Of Anterograde Dense Core Granule Transport
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