ZGPAT and DHX15

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZGPAT	DHX15
Gene Name		zinc finger, CCCH-type with G patch domain	DEAH (Asp-Glu-Ala-His) box helicase 15
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus Cytoplasm U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	RNA Helicase Activity Double-stranded RNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Prostate cancer ( 23535732) Ulcerative colitis ( 21297633)	Myopia (pathological) ( 23049088)
Protein-Protein Interactions		31 interactors: AES AIMP2 AMOTL2 BEND5 BLZF1 CCDC33 CCDC57 CCNDBP1 CEP70 CTNNA1 DHX15 DYDC1 FAM9B GOLGA2 IKZF3 KIFC3 KRT15 KRT40 LDOC1 LZTS2 MID2 MIPOL1 PHC2 SSX2IP STAC3 TFIP11 TP53BP2 TRIM27 TRIM54 UPF2 ZBTB8A	12 interactors: APBB1 DDX42 NKAP PIN1 PINX1 PRPF40A RBM17 TRA2A WBP4 YWHAB YWHAG ZGPAT
Entrez ID		84619	1665
HPRD ID		15736	04553
Ensembl ID		ENSG00000197114	ENSG00000109606
Uniprot IDs		Q8N5A5	O43143
PDB IDs		4II1
Enriched GO Terms of Interacting Partners?		Epithelial Cell-cell Adhesion Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell	RNA Splicing MRNA Processing Gene Expression Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway MRNA Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Cycle RNA Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Cytokinesis Negative Regulation Of Transferase Activity Nucleobase-containing Compound Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Phosphorylation Regulation Of Mitochondrion Organization Regulation Of Protein Phosphorylation Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphorylation Positive Regulation Of Cell Death Intrinsic Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Phosphorus Metabolic Process Cellular Metabolic Process Cellular Response To Insulin Stimulus Negative Regulation Of Protein Kinase Activity Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Regulation Of Protein Kinase Activity Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Kinase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Intracellular Transport Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process
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