ZGPAT and CDCA7L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		ZGPAT	CDCA7L
Description		zinc finger CCCH-type and G-patch domain containing	cell division cycle associated 7 like
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Plasma Membrane	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of DNA-templated Transcription	Regulation Of DNA-templated Transcription Positive Regulation Of Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) High density lipoprotein cholesterol levels ( 31928498) Inflammatory bowel disease ( 23128233 28067908) Lipoprotein (a) levels ( 33730874) Lung function (FEV1) ( 28166213) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Prostate cancer ( 31562322 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633) Waist circumference ( 31928498)	Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		77 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 C1D CARD9 CAVIN4 CCDC13 CCDC196 CCDC33 CCDC57 CCHCR1 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CNKSR1 CTNNA1 DHX15 DVL2 DYDC1 EP400 FAM9B GATAD2B GOLGA2 GOLGA6L9 HOOK2 HSF2BP IHO1 IKZF3 KIAA1328 KIFC3 KRT15 KRT31 KRT40 LCA5L LDOC1 LNX1 LZTS1 LZTS2 MID2 MIPOL1 NEBL PHC2 PPP1R13B PRPF3 S100A10 SCNM1 SERTAD3 SNRPA1 SPAG5 SSX2IP STAC3 TADA2B TFIP11 THAP1 THAP6 TLE5 TP53BP2 TRIM14 TRIM27 TRIM54 UBXN11 UPF2 ZBTB8A ZC2HC1B ZNF177 ZNF24 ZNF329 ZNF426 ZNF559-ZNF177 ZNF587 ZNF688 ZNF71 ZSCAN22 ZXDB	68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 GPRASP3 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821
Entrez ID		84619	55536
HPRD ID		15736	11481
Ensembl ID		ENSG00000197114	ENSG00000164649
Uniprot IDs		A0A0S2Z5X3 Q8N5A5	A8K8X5 Q96GN5
PDB IDs		4II1	5YI9 6EMO
Enriched GO Terms of Interacting Partners?		Protein Binding Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Negative Regulation Of Viral Transcription Cytoskeleton U2-type Post-mRNA Release Spliceosomal Complex Regulation Of RNA Metabolic Process Regulation Of Viral Transcription Microtubule Microtubule Binding Regulation Of Nucleobase-containing Compound Metabolic Process Zonula Adherens	Nucleus RRNA Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding RRNA Processing Regulation Of RNA Metabolic Process Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization RNA Metabolic Process Chromatin Remodeling Chromosome Nucleolus Nucleic Acid Metabolic Process RNA Processing Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Primary Metabolic Process SnoRNA Localization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Myosin Phosphatase Regulator Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Apoptotic Signaling Pathway MOZ/MORF Histone Acetyltransferase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleolus Spliceosomal Complex Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of RNA Metabolic Process Skeletal System Morphogenesis DNA Binding Positive Regulation Of Biosynthetic Process Protein-RNA Complex Assembly Titin Binding Regulation Of DNA Replication Dorsal/ventral Axis Specification Regulation Of Signal Transduction By P53 Class Mediator Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Telomere Maintenance In Response To DNA Damage
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