NVL

Description		nuclear VCP like
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GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Nucleus Nucleoplasm Telomerase Holoenzyme Complex Nucleolus Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Protein-containing Complex Binding Preribosome Binding
	Biological Process	RRNA Processing Positive Regulation Of Protein Binding Positive Regulation Of Telomere Maintenance Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Regulation Of Protein Localization To Nucleolus Telomerase Holoenzyme Complex Assembly
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Major depressive disorder ( 21042317) Mean corpuscular hemoglobin ( 32888494)
Novel Interacting Genes		1 novel interacting genes: NDUFAF1
Interacting Genes		11 interacting genes: ADARB1 CRMP1 FBXO7 HSPB1 LINC00839 OSGEP RNF10 RNF4 RPL5 TTF2 UBE2I
Entrez ID		4931
HPRD ID		03887
Ensembl ID		ENSG00000143748
Uniprot IDs		B4DF43 O15381
PDB IDs		2X8A 6RO1
Enriched GO Terms of Interacting Partners?		Hypoglossal Nerve Morphogenesis Negative Regulation Of Protein Kinase C Signaling Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process SUMO Conjugating Enzyme Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Autoubiquitination Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Double-stranded RNA Adenosine Deaminase Activity Cytoplasm Adenosine To Inosine Editing RNA Processing Spinal Cord Ventral Commissure Morphogenesis Facial Nerve Morphogenesis Cytosol Regulation Of Protein Kinase C Signaling Unfolded Protein Binding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Kinase C Inhibitor Activity Ubiquitin Binding Regulation Of Kinetochore Assembly Post-translational Protein Modification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process SUMO Polymer Binding Protein K48-linked Ubiquitination PML Body Cytosolic Ribosome Negative Regulation Of Protein Neddylation RING-like Zinc Finger Domain Binding SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Lewy Body Core EKC/KEOPS Complex TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity TRNA Threonylcarbamoyladenosine Modification TRNA-specific Adenosine Deaminase Activity Dihydropyrimidinase Activity Regulation Of Centromere Complex Assembly Proteasomal Protein Catabolic Process Negative Regulation Of Protein Localization To Chromatin
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