KLHDC7B and ZC3H10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLHDC7B	ZC3H10
Description		kelch domain containing 7B	zinc finger CCCH-type containing 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	Protein Binding	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding
	Biological Process		Post-transcriptional Regulation Of Gene Expression Regulation Of RNA Splicing Negative Regulation Of MiRNA Processing
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Mean corpuscular hemoglobin ( 20139978) Monocyte count ( 32888494) Red blood cell count ( 29403010) Serum metabolite levels ( 33031748)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		25 interacting genes: A1CF BHLHE40 CFTR DTX2 ESRP1 FNDC3B HNRNPUL1 LIMS3 LIMS4 MAPRE3 NFYC PATZ1 PHC2 POGZ QRICH1 RBPMS RBPMS2 RHOXF2 SMUG1 SPMIP9 TBX6 TLE5 TP53BP1 WWOX ZC3H10	52 interacting genes: ACTMAP ALG13 AOC1 APPBP2 ARID5A ATXN1 BOLL C10orf55 CRX DAB1 DAZAP2 DMRTB1 ESRP1 FAM168B FOSB FOXH1 HIVEP1 INTS11 KLHDC7B KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MIR143 MSX2 NCS1 NFYA OTX2 OXER1 PIAS2 PICALM PLA2G10 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM38 RBPMS RBPMS2 RNF4 SNRPA SPMIP9 STAM2 TENT5A TENT5B UBE2I ZNF34
Entrez ID		113730	84872
HPRD ID		14453	07860
Ensembl ID		ENSG00000130487	ENSG00000135482
Uniprot IDs		A0A3B3ISF6 Q96G42	Q96K80
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding MRNA Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Single-strand Selective Uracil DNA N-glycosylase Activity Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Positive Regulation Of Metabolic Process	Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization Negative Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process MRNA 3'-UTR Binding Regulation Of RNA Stability Regulation Of Primary Metabolic Process MRNA Binding Cytoplasmic Stress Granule Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Poly(A) RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Regulation Of MRNA Processing Positive Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of DNA-templated Transcription Intermediate Filament Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process RNA Binding Transcription Factor Binding SUMO Transferase Activity 3'-UTR-mediated MRNA Stabilization
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