CUL4A and DCUN1D1

Number of citations of the paper that reports this interaction (PMID 18826954)
22

Data Source:
BioGRID (pull down)

		CUL4A	DCUN1D1
Gene Name		cullin 4A	DCN1, defective in cullin neddylation 1, domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Repair Cell Cycle Arrest Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Viral Process Protein Ubiquitination Hemopoiesis Negative Regulation Of Granulocyte Differentiation Somatic Stem Cell Maintenance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Regulation Of Nucleotide-excision Repair	Biological_process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: CAND1 CDKN1B CHEK1 COMMD1 COPS2 COPS5 DCUN1D1 DCUN1D3 DCUN1D4 DCUN1D5 DDB1 DDB2 HIST1H1C HIST1H3A HOXA9 RBX1 RNF7 SALL2 SENP8 SKP2 UBE2E3	21 interactors: ARRDC3 AURKB CALM1 CAND1 CUL2 CUL3 CUL4A CUL4B DAZAP2 LAPTM5 LZTS2 NEDD4 NEDD8 RHOA RNF11 SMAD2 TP53BP2 TRIM39 TRIM54 UBE2F VPS37B
Entrez ID		8451	54165
HPRD ID		07218	12067
Ensembl ID		ENSG00000139842
Uniprot IDs		B2RBV7 Q13619	C9JVE2 Q96GG9
PDB IDs		2HYE 4A0K	3TDU 3TDZ
Enriched GO Terms of Interacting Partners?		Protein Deneddylation Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To UV Protein Monoubiquitination UV-damage Excision Repair Cellular Response To UV Cullin Deneddylation Cellular Protein Modification Process Protein Neddylation Histone H2A Monoubiquitination Cellular Response To Light Stimulus Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Protein Modification By Small Protein Removal Response To Light Stimulus Cellular Response To Radiation Response To Abiotic Stimulus Chromatin Organization Cellular Protein Metabolic Process Protein Polyubiquitination Histone Ubiquitination Response To Radiation Cellular Response To DNA Damage Stimulus Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Stress Chromosome Organization DNA Repair Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription DNA Metabolic Process Cellular Response To Cell-matrix Adhesion Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage SCF Complex Assembly Histone H3-T11 Phosphorylation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleotide-excision Repair Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Catabolic Process Regulation Of Cytokinesis Cellular Macromolecule Catabolic Process Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Cellular Response To Light Stimulus Cellular Protein Modification Process Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Cytokinesis Cellular Response To Radiation Catabolic Process Protein Monoubiquitination Cell Cycle Cleavage Furrow Formation Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Intrinsic Apoptotic Signaling Pathway Proteolysis Cellular Response To UV Protein Neddylation Mitotic Cell Cycle Regulation Of Signal Transduction Response To Radiation Negative Regulation Of Cell Cycle Spindle Midzone Assembly Cellular Protein Metabolic Process Spindle Assembly Regulation Of Cell Division Regulation Of Signaling Developmental Process Viral Process Protein Metabolic Process Cytokinesis Mitotic Nuclear Division Positive Regulation Of Mitotic Cell Cycle Mitotic Spindle Assembly Protein Complex Assembly Cell Cycle Process Positive Regulation Of Cell Division Response To Light Stimulus Spindle Organization Cellular Protein Complex Assembly
Tagcloud ?		aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Difference) ?		aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	achilles adapter adapters amplicons amplifications amplified atlas backgrounds bioinformatics datasets driver druggable emphasis fgfr frs2 gistic2 grb7 hedgehog kras narrowed nsd3 pik3ca projects putative referencing shrna spanning tailoring tcga
Tagcloud (Intersection) ?