CUL4A and HOXA9

Number of citations of the paper that reports this interaction (PMID 14609952)
21

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CUL4A	HOXA9
Gene Name		cullin 4A	homeobox A9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Enzyme Binding Sequence-specific DNA Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Repair Cell Cycle Arrest Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Viral Process Protein Ubiquitination Hemopoiesis Negative Regulation Of Granulocyte Differentiation Somatic Stem Cell Maintenance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Regulation Of Nucleotide-excision Repair	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Endothelial Cell Activation Negative Regulation Of Myeloid Cell Differentiation Embryonic Skeletal System Development Uterus Development Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: CAND1 CDKN1B CHEK1 COMMD1 COPS2 COPS5 DCUN1D1 DCUN1D3 DCUN1D4 DCUN1D5 DDB1 DDB2 HIST1H1C HIST1H3A HOXA9 RBX1 RNF7 SALL2 SENP8 SKP2 UBE2E3	15 interactors: CREBBP CUL4A JUN MEIS1 MEIS2 NFKBIA PBX1 PBX2 PBX3 PLSCR1 RBPMS SMAD2 SMAD4 TRIP6 UBC
Entrez ID		8451	3205
HPRD ID		07218	00844
Ensembl ID		ENSG00000139842	ENSG00000078399
Uniprot IDs		B2RBV7 Q13619	P31269
PDB IDs		2HYE 4A0K
Enriched GO Terms of Interacting Partners?		Protein Deneddylation Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To UV Protein Monoubiquitination UV-damage Excision Repair Cellular Response To UV Cullin Deneddylation Cellular Protein Modification Process Protein Neddylation Histone H2A Monoubiquitination Cellular Response To Light Stimulus Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Protein Modification By Small Protein Removal Response To Light Stimulus Cellular Response To Radiation Response To Abiotic Stimulus Chromatin Organization Cellular Protein Metabolic Process Protein Polyubiquitination Histone Ubiquitination Response To Radiation Cellular Response To DNA Damage Stimulus Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Stress Chromosome Organization DNA Repair Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription DNA Metabolic Process Cellular Response To Cell-matrix Adhesion Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage SCF Complex Assembly Histone H3-T11 Phosphorylation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleotide-excision Repair Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Differentiation Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Stem Cell Maintenance Regulation Of Metabolic Process Regulation Of Myeloid Cell Differentiation Biosynthetic Process Regulation Of Cell Differentiation Somatic Stem Cell Maintenance Negative Regulation Of Myeloid Cell Differentiation Stem Cell Development Stem Cell Differentiation Response To Growth Factor Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Import Into Nucleus Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cell Development Positive Regulation Of Innate Immune Response Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress SMAD Protein Signal Transduction Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of Protein Localization To Nucleus
Tagcloud ?		aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization nih nucleoporin nucleoporins nup153 nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?		aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott	acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization nih nucleoporin nucleoporins nup153 nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?