DHX16 and COIL

Number of citations of the paper that reports this interaction (PubMedID 34079125)
0

Data Source:
BioGRID (proximity labelling technology, two hybrid)
HPRD (two hybrid)

		DHX16	COIL
Description		DEAH-box helicase 16	coilin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Precatalytic Spliceosome Ribonucleoprotein Complex	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity Pattern Recognition Receptor Activity Ubiquitin Binding Molecular Adaptor Activity	Protein Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Immune System Process MRNA Processing RNA Splicing Innate Immune Response Antiviral Innate Immune Response	Spliceosomal SnRNP Assembly
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Height ( 18391951)
Interacting Genes		13 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 MYO19 RIGI RNF10 SNRNP27 TFIP11 XAB2	84 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR1 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 OGT PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		8449	8161
HPRD ID		04555	02605
Ensembl ID		ENSG00000204560	ENSG00000121058
Uniprot IDs		A0A1U9X7L7 B4DZ28 O60231 Q5SQH4 Q5SQH5	P38432
PDB IDs		5Z56 5Z57 5Z58 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U 8I0V
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome RNA Splicing MRNA Processing RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Mitochondrion Migration Along Actin Filament	Cytoplasm Cytosol Nucleoplasm Macromolecule Metabolic Process Nucleic Acid Metabolic Process Spliceosomal SnRNP Assembly Nucleus Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly 7-methylguanosine Cap Hypermethylation Cajal Body Protein Binding Methylosome RNA Metabolic Process Transmembrane Transporter Binding Cytoskeleton Z Disc Pseudopodium Negative Regulation Of DNA Metabolic Process Cyclin E1-CDK2 Complex DNA End Binding Ku70:Ku80 Complex SMN-Sm Protein Complex Small Nuclear Ribonucleoprotein Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Spliceosomal Complex Assembly Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Postsynapse Telomere Maintenance POZ Domain Binding Nucleolus Main Axon DNA-dependent Protein Kinase Complex Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Regulation Of RNA Metabolic Process Macromolecule Methylation DNA-templated Transcription Identical Protein Binding Regulation Of Long-term Neuronal Synaptic Plasticity Protein Modification Process Platelet Alpha Granule Lumen Protein-containing Complex Assembly Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Telomeric DNA Binding Cellular Response To Gamma Radiation RNA Splicing Telomere Organization
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