DHX16 and DGCR14

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		DHX16	DGCR14
Gene Name		DEAH (Asp-Glu-Ala-His) box polypeptide 16	DiGeorge syndrome critical region gene 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm	Nucleus Catalytic Step 2 Spliceosome
	Molecular Function	RNA Helicase Activity ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Molecular_function Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome Nervous System Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP COIL CSNK2A1 DGCR14 MEGF10 SNRNP27 SNRNP40 XAB2	11 interactors: CDK5RAP3 CRP DHX16 FRA10AC1 GNB2L1 LYST PFDN1 RBM4 TTC14 VIM WNK2
Entrez ID		8449	8220
HPRD ID		04555	03452
Ensembl ID		ENSG00000204560	ENSG00000100056
Uniprot IDs		B4DZ28 O60231 Q5SQH4	Q96DF8
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Skeletal Muscle Satellite Cell Proliferation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cell Recognition Skeletal Muscle Cell Proliferation Synaptic Growth At Neuromuscular Junction Skeletal Muscle Satellite Cell Activation Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Axon Choice Point Recognition Skeletal Muscle Satellite Cell Differentiation Regulation Of Cell Cycle Phase Transition Recognition Of Apoptotic Cell Negative Regulation Of Endopeptidase Activity Neuron Remodeling Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Multicellular Organismal Development Negative Regulation Of Protein Processing Phagocytosis, Recognition Regulation Of Endopeptidase Activity Axon Guidance Anatomical Structure Development Cellular Copper Ion Homeostasis Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Mitotic Cell Cycle Copper Ion Homeostasis Suckling Behavior	Negative Regulation Of Translation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of CAMP Catabolic Process Mast Cell Secretory Granule Organization Regulation Of Neuron Differentiation Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Ion Homeostasis Regulation Of Cell Differentiation IRES-dependent Translational Initiation Cap-independent Translational Initiation Regulation Of Neurogenesis Endosome Transport Via Multivesicular Body Sorting Pathway Circadian Regulation Of Translation Defense Response To Bacterium Negative Regulation Of Oxidative Stress-induced Neuron Death Bergmann Glial Cell Differentiation Negative Regulation Of Vasodilation Secretion Of Lysosomal Enzymes Protein Ufmylation Negative Regulation Of Translation In Response To Stress Regulation Of Cell Development Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Phospholipid Homeostasis Regulation Of Gene Expression Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Cytoplasmic Translational Initiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death Positive Regulation Of Mitochondrial Depolarization Opsonization Leukocyte Mediated Immunity Adaptive Immune Response Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Phagocytosis Regulation Of Translation Cell Differentiation Central Nervous System Development Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Superoxide Anion Generation Regulation Of Interleukin-8 Secretion Regulation Of Cellular Localization Rhythmic Process Regulation Of Metabolic Process Cytoplasmic Translation Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Translation In Response To Stress Negative Regulation Of Macrophage Derived Foam Cell Differentiation
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