DHX16 and MYO19

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		DHX16	MYO19
Description		DEAH-box helicase 16	myosin XIX
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Precatalytic Spliceosome Ribonucleoprotein Complex	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Cytoskeleton Actin Cytoskeleton Membrane Myosin Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity Pattern Recognition Receptor Activity Ubiquitin Binding Molecular Adaptor Activity	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding ATP Binding Cytoskeletal Protein Binding ATP Hydrolysis Activity Myosin Light Chain Binding Actin Filament Binding Plus-end Directed Microfilament Motor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Immune System Process MRNA Processing RNA Splicing Innate Immune Response Antiviral Innate Immune Response	Endocytosis Actin Filament Organization Regulation Of Cytokinesis Mitochondrion Migration Along Actin Filament Establishment Of Mitochondrion Localization Regulation Of Mitochondrial Fission Mitocytosis
Pathways		mRNA Splicing - Major Pathway	RHOT2 GTPase cycle RHOT1 GTPase cycle
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Body mass index ( 26426971 28552196 29273807) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31015462 31152163)
Interacting Genes		13 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 MYO19 RIGI RNF10 SNRNP27 TFIP11 XAB2	1 interacting genes: DHX16
Entrez ID		8449	80179
HPRD ID		04555	10107
Ensembl ID		ENSG00000204560	ENSG00000278259
Uniprot IDs		A0A1U9X7L7 B4DZ28 O60231 Q5SQH4 Q5SQH5	B4E218 B7Z1T7 Q96H55
PDB IDs		5Z56 5Z57 5Z58 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U 8I0V
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome RNA Splicing MRNA Processing RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Mitochondrion Migration Along Actin Filament	Cytotoxic T Cell Pyroptotic Cell Death ATP-dependent Activity, Acting On RNA Defense Response To Other Organism Defense Response To Symbiont Pyroptotic Cell Death Wide Pore Channel Activity Granzyme-mediated Programmed Cell Death Signaling Pathway Cardiolipin Binding Defense Response Pattern Recognition Receptor Activity Response To Other Organism Response To External Biotic Stimulus U2-type Precatalytic Spliceosome Biological Process Involved In Interaction With Symbiont Phosphatidylinositol-4-phosphate Binding Pyroptotic Inflammatory Response Killing By Host Of Symbiont Cells Phosphatidylserine Binding Antiviral Innate Immune Response RNA Helicase Activity Phosphatidylinositol-4,5-bisphosphate Binding Defense Response To Gram-negative Bacterium Ubiquitin Binding Helicase Activity Killing Of Cells Of Another Organism Phospholipid Binding
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