DYDC2 and POLR1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYDC2	POLR1A
Description		DPY30 domain containing 2	RNA polymerase I subunit A
Image
GO Annotations	Cellular Component	Set1C/COMPASS Complex	DNA-directed RNA Polymerase Complex Chromatin Nucleus Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex
	Molecular Function	Protein Binding	Magnesium Ion Binding DNA Binding Chromatin Binding DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity 5'-3' RNA Polymerase Activity Metal Ion Binding DNA/RNA Hybrid Binding
	Biological Process		DNA-templated Transcription Transcription By RNA Polymerase I Nucleolar Large RRNA Transcription By RNA Polymerase I Negative Regulation Of Protein Localization To Nucleolus
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Facial emotion recognition (sad faces) ( 28608620)
Interacting Genes		5 interacting genes: DPY30 NME5 POLR1A TENT5D UBXN2A	10 interacting genes: ANP32B DYDC2 MEOX2 NFKBIB NOLC1 POLR1E PTEN RRN3 SKP2 TCF4
Entrez ID		84332	25885
HPRD ID		11311	10161
Ensembl ID		ENSG00000133665	ENSG00000068654
Uniprot IDs		A0A0A0MRQ7 Q96IM9	O95602
PDB IDs		8J07	7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43
Enriched GO Terms of Interacting Partners?			Protein-DNA Complex Assembly Nucleolus Organization Transcription Initiation At RNA Polymerase I Promoter RNA Polymerase I Preinitiation Complex Assembly RNA Polymerase Binding Molecular Function Inhibitor Activity Nucleolus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Synaptic Vesicle Clustering Transcription Preinitiation Complex Assembly RNA Polymerase I General Transcription Initiation Factor Binding Positive Regulation Of Macromolecule Metabolic Process Roof Of Mouth Development Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Negative Regulation Of Adaptive Immune Memory Response DNA-templated Transcription Initiation Nucleus Organization Beta-catenin Binding Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Beta-catenin-TCF7L2 Complex RNA Polymerase I Core Binding Positive Regulation Of Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?