DYDC2 and NME5

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		DYDC2	NME5
Description		DPY30 domain containing 2	NME/NM23 family member 5
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GO Annotations	Cellular Component	Set1C/COMPASS Complex	Radial Spoke Extracellular Region Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection 9+2 Motile Cilium
	Molecular Function	Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding 3'-5'-DNA Exonuclease Activity Hydrolase Activity
	Biological Process		Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process DNA Catabolic Process Spermatogenesis Spermatid Development Nucleoside Metabolic Process Ventricular System Development Cell Differentiation Spermatid Differentiation Establishment Of Localization In Cell Cilium Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Atrial fibrillation ( 29892015) Autism spectrum disorder or schizophrenia ( 28540026) Carboplatin disposition in epthelial ovarian cancer ( 29367611)
Interacting Genes		5 interacting genes: DPY30 NME5 POLR1A TENT5D UBXN2A	4 interacting genes: CEP76 DYDC1 DYDC2 ZYX
Entrez ID		84332	8382
HPRD ID		11311	04655
Ensembl ID		ENSG00000133665	ENSG00000112981
Uniprot IDs		A0A0A0MRQ7 Q96IM9	A0A0S2Z4L9 P56597
PDB IDs		8J07	8J07
Enriched GO Terms of Interacting Partners?			Set1C/COMPASS Complex
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