YIPF4 and BIK

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		YIPF4	BIK
Description		Yip1 domain family member 4	BCL2 interacting killer
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Endomembrane System Membrane	Mitochondrion Endomembrane System Membrane Mitochondrial Membrane Bcl-2 Family Protein Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Male-pattern baldness ( 28196072) Refractive error ( 32231278)	Prostate cancer ( 21743057 25939597) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		37 interacting genes: AQP6 ARL6IP1 BIK CD79A CNR2 CYB5R3 EBP ERGIC3 FAM209A FATE1 FCER1G FKBP7 GPR152 GPR42 HSD17B13 IER3IP1 NAT8 REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC18A1 SLC30A8 SLC35A4 SLC35H1 SLC71A2 SLC7A1 SLC7A14 TIMMDC1 TLCD4 TMEM14B TSNARE1 TVP23B YIF1A YIPF3 ZDHHC15	116 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ARLN ASB11 ATP13A1 BCL2 BCL2A1 BCL2L1 BCL2L2 BET1 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 CD53 CD72 CDS2 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB561D2 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A FKBP8 GOSR2 GPX8 GRM2 HMOX2 IGFBP5 INSIG2 KCNN4 LNPEP MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM ORMDL1 ORMDL2 PBX3 PEX16 PGAP2 PGRMC1 PLLP PLN PLP1 PLP2 PLPP4 PMP22 REEP4 REEP6 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 SYNGR1 TANK TMBIM1 TMEM107 TMEM11 TMEM147 TMEM14B TMEM14C TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBIAD1 UPK1B VAMP3 VAMP4 VAMP5 VAPA VAPB VMA12 VTI1B YIPF4 ZFPL1
Entrez ID		84272	638
HPRD ID		14410	04547
Ensembl ID		ENSG00000119820	ENSG00000100290
Uniprot IDs		Q9BSR8	Q13323
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Transmembrane Transport Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Transmembrane Transporter Activity Zinc:proton Antiporter Activity Mitochondrial Membrane COPII-coated ER To Golgi Transport Vesicle Ubiquitin-like Protein Conjugating Enzyme Binding Pyrimidine Nucleotide-sugar Transmembrane Transport Zinc Ion Import Into Organelle Nucleotide-sugar Transmembrane Transport Serotonin Transport Endoplasmic Reticulum Organization Endoplasmic Reticulum Mannose Trimming Golgi Membrane Protein Alpha-1,2-demannosylation Monoatomic Cation Transmembrane Transporter Activity Insulin Metabolic Process Endoplasmic Reticulum-Golgi Intermediate Compartment Protein Deglycosylation Endoplasmic Reticulum Tubular Network Organization Protein Binding Endoplasmic Reticulum Tubular Network Zinc Ion Transmembrane Transporter Activity Endoplasmic Reticulum Quality Control Compartment Antiporter Activity Zinc Ion Transmembrane Transport	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Organelle Fusion Protein Binding Membrane Organization Mitochondrial Outer Membrane SNAP Receptor Activity Bcl-2 Family Protein Complex Release Of Cytochrome C From Mitochondria SNARE Complex Vesicle-mediated Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Membrane Fusion Vesicle Organization Endomembrane System Regulation Of Cellular Localization Golgi Vesicle Transport Chemical Homeostasis Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Vesicle Fusion BH3 Domain Binding Apoptotic Mitochondrial Changes Organelle Membrane Fusion Cellular Homeostasis Channel Activity Vesicle Fusion With Golgi Apparatus Intracellular Chemical Homeostasis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Membrane Docking Pigment Metabolic Process Presynaptic Endosome Membrane Intracellular Monoatomic Cation Homeostasis Response To Cytokine Heme Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Intracellular Monoatomic Ion Homeostasis Response To Peptide Regulation Of Transport Homeostatic Process Inorganic Ion Homeostasis Dendritic Cell Apoptotic Process Ascorbate Homeostasis FFAT Motif Binding Oxysterol Binding Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Membrane Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Localization
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