TBC1D3F and RAB5A

Number of citations of the paper that reports this interaction (PMID 12612085)
10

Data Source:
HPRD (in vivo)

		TBC1D3F	RAB5A
Gene Name		TBC1 domain family, member 3F	RAB5A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Ruffle Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Actin Cytoskeleton Endocytic Vesicle Axon Dendrite Somatodendritic Compartment Melanosome Zymogen Granule Membrane Neuronal Cell Body Terminal Bouton Protein Complex Axon Terminus Membrane Raft Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Cytoplasmic Side Of Early Endosome Membrane
	Molecular Function	Rab GTPase Activator Activity	GTPase Activity Protein Binding GTP Binding GDP Binding GDP-dissociation Inhibitor Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Endocytosis Rab Protein Signal Transduction Synaptic Vesicle Recycling Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Endosome Size Regulation Of Filopodium Assembly Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		4 interactors: CDC42 RAB5A RAC1 YWHAE	41 interactors: AGTR1 ALS2CL ANKFY1 AP1G1 AP1G2 APPL1 APPL2 CHM CHML EEA1 GDI2 GGA1 GGA2 GGA3 GRIK4 ITSN1 NME2 OCRL RAB37 RAB7A RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 SUN2 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TSC2 USP6NL
Entrez ID		84218	5868
HPRD ID		09667	01542
Ensembl ID		ENSG00000185128	ENSG00000144566
Uniprot IDs		A6NER0 B4DXP2 F5GZ95 Q8IZP1	B4DJA5 P20339
PDB IDs			1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Projection Assembly Wnt Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Cellular Protein Localization Substantia Nigra Development Blood Coagulation Hemostasis Regulation Of Filopodium Assembly Regulation Of Phosphatidylinositol 3-kinase Activity Neural Nucleus Development Regulation Of Cell Projection Organization Regulation Of Lipid Kinase Activity Intracellular Signal Transduction Protein Localization Positive Regulation Of DNA Replication Regulation Of Cellular Component Organization Regulation Of Body Fluid Levels T Cell Costimulation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Wound Healing Positive Regulation Of Cell Death Small GTPase Mediated Signal Transduction Midbrain Development Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Canonical Wnt Signaling Pathway Ephrin Receptor Signaling Pathway Response To Wounding Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Localization Positive Regulation Of Transport Brain Development Positive Regulation Of Cell-substrate Adhesion Head Development Regulation Of DNA Replication Cell Migration Epidermal Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of DNA Metabolic Process Regulation Of Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cerebral Cortex Development Central Nervous System Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation	Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Vesicle-mediated Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Protein Transport Protein Localization Establishment Of Protein Localization Establishment Of Localization In Cell Intracellular Transport Transport Cellular Localization Endocytosis Intracellular Protein Transport Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Endosomal Transport Regulation Of Signaling Regulation Of Signal Transduction Membrane Organization Cellular Protein Localization Protein Geranylgeranylation Regulation Of Vesicle-mediated Transport Regulation Of Metabolic Process Vesicle Fusion Membrane Fusion Positive Regulation Of Exocytosis Protein Prenylation Regulation Of Exocytosis Organelle Fusion Golgi To Lysosome Transport Vesicle Organization Intracellular Signal Transduction Ras Protein Signal Transduction Lysosomal Transport Golgi To Vacuole Transport Plasma Membrane To Endosome Transport Cytoplasmic Transport Signaling Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion
Tagcloud ?			accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Difference) ?			accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Intersection) ?