UNC5CL and KRTAP13-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UNC5CL	KRTAP13-2
Description		unc-5 family C-terminal like	keratin associated protein 13-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Netrin Receptor Activity Protein Binding Peptidase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Signal Transduction Netrin-activated Signaling Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade
Pathways			Keratinization
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 33589840) Esophageal cancer ( 21642993) Gastric cancer ( 26129866) Non-cardia gastric cancer ( 26129866) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: KRTAP13-2 KRTAP6-1 NFKB1 PGAM1 RELA TOX2 ZMYND12	81 interacting genes: ANAPC11 ANXA11 BCL6 C22orf39 CBFA2T2 CCDC125 CCDC24 CCDC57 CCNK CFAP68 CRYBA1 CSKMT CYSRT1 ENKD1 EPDR1 ETFDH FANCL FBXO17 FCHO1 GATA3 GEMIN4 GNE GPS2 GRN HNRNPH1 HOXA1 HR KCTD9 KLHL38 KPRP KRT3 KRTAP1-1 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-4 KRTAP4-5 KRTAP9-2 MAGOHB MEOX2 MGAT5B NBPF19 NEK8 NHLRC4 NOTCH2NLA OIP5 OTX1 P4HB PATZ1 PHETA1 PITX1 POU2AF1 RECK RHOXF2 SAXO4 SLC25A18 SLIT1 SMUG1 SNRPC SPEF1 SPMIP9 SSC4D STK16 TCAF1 TLE5 TNS2 TRAPPC6A TRIM68 TSPYL6 TSSK3 UNC5CL VGLL3 VWC2 YPEL3 ZIC1
Entrez ID		222643	337959
HPRD ID		09844	11201
Ensembl ID		ENSG00000124602	ENSG00000182816
Uniprot IDs		H8YHX0 Q8IV45	Q52LG2
PDB IDs
Enriched GO Terms of Interacting Partners?		NF-kappaB P50/p65 Complex Cellular Response To Nicotine Cellular Response To Angiotensin Actinin Binding Cellular Response To Interleukin-6 Response To Interleukin-6 Response To Muscle Stretch Response To Angiotensin Non-canonical NF-kappaB Signal Transduction Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Cytokine Production Involved In Inflammatory Response Response To Nicotine Transcription Coactivator Binding Tumor Necrosis Factor-mediated Signaling Pathway Canonical NF-kappaB Signal Transduction Positive Regulation Of MiRNA Metabolic Process Regulation Of Interleukin-12 Production Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of MiRNA Metabolic Process Chromatin DNA Binding Cellular Response To Tumor Necrosis Factor Response To Tumor Necrosis Factor Positive Regulation Of Hyaluronan Biosynthetic Process Secretory Granule Lumen I-kappaB/NF-kappaB Complex Phosphoglycerate Mutase Activity Bisphosphoglycerate Mutase Activity Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin Negative Regulation Of Vitamin D Biosynthetic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Intermediate Filament Mammary Gland Involution Postsynapse To Nucleus Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Response To Mechanical Stimulus Regulation Of Hyaluronan Biosynthetic Process Ankyrin Repeat Binding Cellular Response To Peptidoglycan Cellular Response To Interleukin-17 Intramolecular Phosphotransferase Activity Transcription Regulator Complex Regulation Of Vitamin Metabolic Process Defense Response To Tumor Cell Negative Regulation Of Protein Sumoylation	Intermediate Filament Keratin Filament Protein Binding
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