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UNC5CL
Description
unc-5 family C-terminal like
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Membrane
Molecular Function
Netrin Receptor Activity
Protein Binding
Peptidase Activity
Biological Process
Signal Transduction
Netrin-activated Signaling Pathway
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS
Alzheimer's disease or family history of Alzheimer's disease (
33589840
)
Esophageal cancer (
21642993
)
Gastric cancer (
26129866
)
Non-cardia gastric cancer (
26129866
)
Urate levels (
31578528
)
Interacting Genes
7 interacting genes:
KRTAP13-2
KRTAP6-1
NFKB1
PGAM1
RELA
TOX2
ZMYND12
Entrez ID
222643
HPRD ID
09844
Ensembl ID
ENSG00000124602
Uniprot IDs
H8YHX0
Q8IV45
PDB IDs
Enriched GO Terms of Interacting Partners
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NF-kappaB P50/p65 Complex
Cellular Response To Nicotine
Cellular Response To Angiotensin
Actinin Binding
Cellular Response To Interleukin-6
Response To Interleukin-6
Response To Muscle Stretch
Response To Angiotensin
Non-canonical NF-kappaB Signal Transduction
Signal Transduction Involved In Regulation Of Gene Expression
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Response To Nicotine
Transcription Coactivator Binding
Tumor Necrosis Factor-mediated Signaling Pathway
Canonical NF-kappaB Signal Transduction
Positive Regulation Of MiRNA Metabolic Process
Regulation Of Interleukin-12 Production
Regulation Of Cytokine Production Involved In Inflammatory Response
Regulation Of MiRNA Metabolic Process
Chromatin DNA Binding
Cellular Response To Tumor Necrosis Factor
Response To Tumor Necrosis Factor
Positive Regulation Of Hyaluronan Biosynthetic Process
Secretory Granule Lumen
I-kappaB/NF-kappaB Complex
Phosphoglycerate Mutase Activity
Bisphosphoglycerate Mutase Activity
Positive Regulation Of Schwann Cell Differentiation
Response To Cobalamin
Negative Regulation Of Vitamin D Biosynthetic Process
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Regulation Of Schwann Cell Differentiation
NF-kappaB Complex
Prolactin Signaling Pathway
Intermediate Filament
Mammary Gland Involution
Postsynapse To Nucleus Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Lipopolysaccharide
Cellular Response To Molecule Of Bacterial Origin
Response To Mechanical Stimulus
Regulation Of Hyaluronan Biosynthetic Process
Ankyrin Repeat Binding
Cellular Response To Peptidoglycan
Cellular Response To Interleukin-17
Intramolecular Phosphotransferase Activity
Transcription Regulator Complex
Regulation Of Vitamin Metabolic Process
Defense Response To Tumor Cell
Negative Regulation Of Protein Sumoylation
Tagcloud
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