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PCGF6 and CBX7
Number of citations of the paper that reports this interaction (PubMedID
33961781
)
97
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)
PCGF6
CBX7
Description
polycomb group ring finger 6
chromobox 7
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Chromatin
Nucleus
Nucleoplasm
Cytosol
PcG Protein Complex
PRC1 Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Pathways
Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (MOSTest) (
32665545
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Schizophrenia (
23974872
25056061
29483656
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Immunoglobulin light chain (AL) amyloidosis (
28025584
)
Lymphocyte count (
27863252
32888494
)
Menarche (age at onset) (
25231870
)
Multiple myeloma (
23955597
26007630
33875642
)
Multiple myeloma and monoclonal gammopathy (
26007630
)
Neutrophil count (
32888494
)
White blood cell count (
27863252
32888494
)
Interacting Genes
27 interacting genes:
BMI1
CBX6
CBX7
CDK7
E2F6
EIF2B2
H3-4
KDM5D
MAGEA1
MAGEC2
MAGEE2
MAGEL2
MYC
OGT
PEX10
PNMA1
RAD18
RNF2
SS18L1
TRIM14
TRIM55
TRIM63
TULP3
UBE2D3
UBE2U
USP2
USP21
12 interacting genes:
B3GNT5
H3-3A
H3-4
H3C1
H3C14
PCGF1
PCGF5
PCGF6
RING1
RNF2
SUV39H2
ZRANB1
Entrez ID
84108
23492
HPRD ID
07427
12234
Ensembl ID
ENSG00000156374
ENSG00000100307
Uniprot IDs
Q9BYE7
B0QYP2
O95931
Q4PNR6
PDB IDs
2DJB
2K1B
2L12
2L1B
3GS2
4MN3
5EPJ
6V2R
8SII
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of DNA-templated Transcription
PRC1 Complex
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Post-translational Protein Modification
Nucleus
Negative Regulation Of RNA Metabolic Process
PcG Protein Complex
Regulation Of Primary Metabolic Process
Chromatin Organization
Regulation Of Gene Expression
Regulation Of Transcription By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Protein Metabolic Process
Ubiquitin Protein Ligase Activity
Heterochromatin
Protein Modification Process
Protein Ubiquitination
Regulation Of Metabolic Process
RING-like Zinc Finger Domain Binding
Protein Modification By Small Protein Conjugation
Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleoplasm
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Protein Polyubiquitination
Protein Monoubiquitination
Positive Regulation Of Ubiquitin-protein Transferase Activity
Nuclear Body
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis
Chromatin Remodeling
Protein Deubiquitination
Chromosome
Ubiquitin-protein Transferase Activity
Macromolecule Metabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Proteasomal Protein Catabolic Process
Protein Modification By Small Protein Removal
Epigenetic Regulation Of Gene Expression
Transferase Activity
MLL1 Complex
Chromatin Remodeling
PRC1 Complex
Chromatin Organization
PcG Protein Complex
Structural Constituent Of Chromatin
Nucleoplasm
Nucleosome Assembly
Epigenetic Regulation Of Gene Expression
Nucleosome
Nucleosome Organization
Histone H2AK119 Ubiquitin Ligase Activity
Chromosome
Protein-DNA Complex Assembly
Sex Chromatin
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Protein Heterodimerization Activity
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Zinc Ion Binding
Negative Regulation Of Metabolic Process
Nucleus
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Heterochromatin
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Activity
Regulation Of Gene Expression
Gene Expression
Regulation Of Macromolecule Biosynthetic Process
RING-like Zinc Finger Domain Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Chromosome Condensation
Regulation Of Macromolecule Metabolic Process
Ubiquitin Ligase Complex
Spermatogonial Cell Division
Protein K29-linked Deubiquitination
Histone H3K9 Trimethyltransferase Activity
X Chromosome
Pericentric Heterochromatin Formation
Telomere Organization
Protein K33-linked Deubiquitination
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Chromatin Binding
Regulation Of Centromere Complex Assembly
Heterochromatin Formation
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Tagcloud (Intersection)
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