PCGF6 and CBX6

Number of citations of the paper that reports this interaction (PubMedID 21282530)
78

Data Source:
BioGRID (pull down)

		PCGF6	CBX6
Description		polycomb group ring finger 6	chromobox 6
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Chromatin Heterochromatin Nucleus Nucleoplasm Chromosome Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Chromatin Binding Single-stranded RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization
Pathways		Transcriptional Regulation by E2F6	Oxidative Stress Induced Senescence RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061 29483656)	Bladder cancer ( 20972438 24163127) Plateletcrit ( 32888494)
Interacting Genes		27 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 MYC OGT PEX10 PNMA1 RAD18 RNF2 SS18L1 TRIM14 TRIM55 TRIM63 TULP3 UBE2D3 UBE2U USP2 USP21	7 interacting genes: H3-3A H3C1 H3C14 HOXC9 PCGF2 PCGF6 RNF2
Entrez ID		84108	23466
HPRD ID		07427	13005
Ensembl ID		ENSG00000156374	ENSG00000183741
Uniprot IDs		Q9BYE7	B0QXZ6 O95503
PDB IDs		2DJB	3GV6 3I90
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription PRC1 Complex Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Post-translational Protein Modification Nucleus Negative Regulation Of RNA Metabolic Process PcG Protein Complex Regulation Of Primary Metabolic Process Chromatin Organization Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Ubiquitin Protein Ligase Activity Heterochromatin Protein Modification Process Protein Ubiquitination Regulation Of Metabolic Process RING-like Zinc Finger Domain Binding Protein Modification By Small Protein Conjugation Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Protein Polyubiquitination Protein Monoubiquitination Positive Regulation Of Ubiquitin-protein Transferase Activity Nuclear Body Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Proteolysis Chromatin Remodeling Protein Deubiquitination Chromosome Ubiquitin-protein Transferase Activity Macromolecule Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Proteasomal Protein Catabolic Process Protein Modification By Small Protein Removal Epigenetic Regulation Of Gene Expression Transferase Activity MLL1 Complex	Chromatin Remodeling PRC1 Complex Chromatin Organization PcG Protein Complex Sex Chromatin Structural Constituent Of Chromatin Nucleosome Assembly Nucleosome Nucleosome Organization Nucleoplasm Protein-DNA Complex Assembly Chromosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Epigenetic Regulation Of Gene Expression Gene Expression Embryonic Skeletal System Development Protein Heterodimerization Activity Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Pattern Specification Process DNA Binding Chromatin Embryonic Skeletal System Morphogenesis Embryonic Morphogenesis Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Chromatin Binding Nucleus Skeletal System Morphogenesis Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Telomere Organization Embryonic Organ Morphogenesis Negative Regulation Of Macromolecule Metabolic Process RING-like Zinc Finger Domain Binding Negative Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Chromosome Condensation Histone H2AK119 Ubiquitin Ligase Activity Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Anterior/posterior Pattern Specification Pericentric Heterochromatin Formation Regulation Of Centromere Complex Assembly Skeletal System Development Germ Cell Development Barr Body
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?