GRHL3

Description		grainyhead like transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Cilium Actin Cytoskeleton
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Pattern Specification Process Ectoderm Development Central Nervous System Development Epidermis Development Gene Expression Positive Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Wound Healing Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Eyelid Development In Camera-type Eye Establishment Of Skin Barrier Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS		Cleft palate ( 27018472) Fasting blood insulin (BMI interaction) ( 22581228) Male-pattern baldness ( 28196072) Response to interferon beta in multiple sclerosis ( 26644207)
Interacting Genes		8 interacting genes: EAF1 ENKD1 GRHL1 GRHL2 PRMT1 PRMT5 PRMT6 RIPPLY1
Entrez ID		57822
HPRD ID		12210
Ensembl ID		ENSG00000158055
Uniprot IDs		Q8TE85
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H4R3 Methyltransferase Activity Protein-arginine N-methyltransferase Activity Histone Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Methylosome Regulation Of DNA-templated Transcription Methyltransferase Activity Regulation Of RNA Biosynthetic Process Histone H3 Methyltransferase Activity Methyl-CpG Binding Regulation Of RNA Metabolic Process Methylation Protein Methylation Regulation Of Megakaryocyte Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process GATOR1 Complex Binding Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Histone H2AR3 Methyltransferase Activity Epithelium Migration Regulation Of Gene Expression Chromatin DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Peptidyl-arginine N-methylation Histone H3R2 Methyltransferase Activity Macromolecule Methylation Protein-arginine Omega-N Symmetric Methyltransferase Activity Regulation Of Signal Transduction By P53 Class Mediator Epithelial Cell Morphogenesis Involved In Placental Branching Intronic Transcription Regulatory Region Sequence-specific DNA Binding N-methyltransferase Activity Regulation Of Macromolecule Metabolic Process Epidermis Development Anterior Neural Tube Closure Positive Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Dopamine Receptor Signaling Pathway Somite Specification Regulation Of Multicellular Organismal Development Nucleoplasm Chromatin Remodeling Cellular Response To Methionine Super Elongation Complex Cell-cell Junction Organization Regulation Of Hemoglobin Biosynthetic Process Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4 Methyltransferase Activity
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